2(3H)-Furanone, 5-dodecyldihydro-

Base Information

• Chemical Name: 2(3H)-Furanone, 5-dodecyldihydro-
• CAS No.: 730-46-1
• Molecular Formula: C₁₆H₃₀O₂
• Molecular Weight: 254.413
• NSC Number: 33746
• DSSTox Substance ID: DTXSID30862390
• Nikkaji Number: J103.580K
• Wikidata: Q67879898
• Metabolomics Workbench ID: 44704
• Mol file: 730-46-1.mol

Synonyms:2(3H)-Furanone, 5-dodecyldihydro-;730-46-1;5-dodecyloxolan-2-one;gamma-Palmitolactone;5-Dodecyldihydro-2(3H)-furanone;Hexadeca-1,4-lactone;.gamma.-Palmitolactone;5-Dodecyldihydrofuran-2(3H)-one;Hexadecanoic acid, 4-hydroxy-, .gamma.-lactone;NSC 33746;2(3H)-Furanone, 5-dodecyldihydro- (9CI);g-Palmitolactone;4-hexadecanolide;NSC33746;.gamma.-Hexadecalactone;starbld0023054;Palmito-.gamma.-lactone;4-Dodecyl-g-butyrolactone;SCHEMBL1029290;laquo gammaRaquo -palmitolactone;laquo gammaRaquo -hexadecalactone;DTXSID30862390;Palmito-laquo gammaRaquo -lactone;CHEBI:170094;gamma-Hydroxypalmitic acid lactone;Hexadecanoic acid, .gamma.-lactone;5-Dodecyldihydro-2(3H)-furanone #;NSC-33746;Hexadecanoic acid, 4-hydroxy-, gamma-lactone;Hexadecanoic acid, 4-hydroxy-, gamma-lactone (8CI);Q67879898;Hexadecanoic acid, 4-hydroxy-, laquo gammaRaquo -lactone

Chemical Property of 2(3H)-Furanone, 5-dodecyldihydro-

Chemical Property:

• Vapor Pressure: 4.78E-05mmHg at 25°C
• Melting Point: 40.7-41.3 °C
• Boiling Point: 349.2°C at 760 mmHg
• Flash Point: 145.4°C
• PSA: 26.30000
• Density: 0.912g/cm³
• LogP: 5.00300
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 11
• Exact Mass: 254.224580195
• Heavy Atom Count: 18
• Complexity: 213

Purity/Quality:

98.5% ^*data from raw suppliers

5-Dodecyldihydro-2(3H)-Furanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCC1CCC(=O)O1
• Uses: 5-dodecyldihydro-2(3H)-Furanone, is a volatile organic compound produced by cooking meats and oils.

Technology Process of 2(3H)-Furanone, 5-dodecyldihydro-

There total 8 articles about 2(3H)-Furanone, 5-dodecyldihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.5%

4-keto-hexadecanoic acid (4144-56-3) → γ-palmitolactone (730-46-1)

Guidance literature:

With sodium hydroxide; sodium tetrahydroborate; In ethanol; for 3h; Ambient temperature;

Reference yield: 57.0%

cis-9-hexadecenoic acid (373-49-9,2091-29-4) → γ-palmitolactone (730-46-1)

Guidance literature:

With silver trifluoromethanesulfonate; In chlorobenzene; at 130 ℃; for 24h; regioselective reaction; Inert atmosphere;

DOI:10.1039/b916853b

Reference yield: 55.0%

oxacyclononadecan-2-one (4444-85-3) → γ-palmitolactone (730-46-1)

Guidance literature:

With W(OTf)₆; at 180 ℃; for 24h; Time; Schlenk technique; Ionic liquid; Inert atmosphere; Green chemistry;

DOI:10.1002/cssc.201800587

upstream raw materials:

(E)-hexadec-3-enenitrile

4-keto-hexadecanoic acid

tridecanal

ethyl acrylate

Refernces

• 1、 Goossen, Lukas J.,Ohlmann, Dominik M.,Dierker, Markus. "Silver triflate-catalysed synthesis of γ-lactones from fatty acids". supporting information; experimental part. p. 197 - 200. Retrieved 2011/02/27.
• 2、 Granata, Alessandro,Perlin, Arthur S.. "Formation of isomeric monohalo-n-alkanoic acids in the reactions of γ- and δ-n-alkanolactones with hydrogen halides". . p. 864 - 871. Retrieved 2007/10/02.