2-Methylbutanal 2,4-Dinitrophenylhydrazone

Base Information

• Chemical Name: 2-Methylbutanal 2,4-Dinitrophenylhydrazone
• CAS No.: 1646-99-7
• Molecular Formula: C11H14N4O4
• Molecular Weight: 266.257
• DSSTox Substance ID: DTXSID30497388
• Mol file: 1646-99-7.mol

Synonyms:(+-)-2-Methyl-butyraldehyd-(2,4-dinitro-phenylhydrazon);2.4-Dinitro-phenylhydrazon des 2-Methyl-butyraldehyds;2.4-Dinitro-phenylhydrazon d. 2-Methyl-butyraldehyds;|A-Methylbutyraldehyde 2,4-Dinitrophenylhydrazone;2-Methylbutanal 2-(2,4-Dinitrophenyl)hydrazone;(+-)-2-methyl-butyraldehyde-(2,4-dinitro-phenylhydrazone);2-methylbutanal (2,4-dinitrophenyl)hydrazone;

Chemical Property of 2-Methylbutanal 2,4-Dinitrophenylhydrazone

Chemical Property:

• Melting Point: 123 - 124°C
• PSA: 116.03000
• LogP: 4.06620
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly)
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 266.10150494
• Heavy Atom Count: 19
• Complexity: 350

Purity/Quality:

99% ^*data from raw suppliers

2-Methylbutanal2,4-Dinitrophenylhydrazone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C)C=NNC1=C(C=C(C=C1)[N+](=O)[O-])[N+](=O)[O-]
• Isomeric SMILES: CCC(C)/C=N/NC1=C(C=C(C=C1)[N+](=O)[O-])[N+](=O)[O-]

Technology Process of 2-Methylbutanal 2,4-Dinitrophenylhydrazone

There total 10 articles about 2-Methylbutanal 2,4-Dinitrophenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

2-Methylbutylamine (96-15-1) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → 2-methylbutanal (2,4-dinitrophenyl)hydrazone (1646-99-7)

Guidance literature:

2-Methylbutylamine; With lithium perchlorate; [3-amino-2,4-dihydroxyphenyl]phenylmethanone; In methanol; at 20 ℃; Electrochemical reaction;

(2,4-dinitro-phenyl)-hydrazine; With sulfuric acid; lithium perchlorate; In methanol; ethanol; for 1h;

DOI:10.1002/anie.200390263

Reference yield:

2-Methylbutyraldehyde (96-17-3,57456-98-1) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → 2-methylbutanal (2,4-dinitrophenyl)hydrazone (1646-99-7)

Guidance literature:

DOI:10.1021/ja01206a020

Reference yield:

(2S)-2-methyl-1-butanol (1565-80-6) → (S)-2-methyl-1-butanal 2,4-dinitrophenylhydrazone (1646-99-7,1730-96-7,33204-49-8,74365-32-5,74365-33-6)

Guidance literature:

Multi-step reaction with 2 steps

1: cromic anhydride-pyridine / CH₂Cl₂

With chromium trioxide-pyridine complex; In dichloromethane;

upstream raw materials:

(R)-2-methyl-butyraldehyde-(2,4-dinitro-phenylhydrazone)

2,4-dinitrophenylhydrazone of (2S)-2-methyl-1-butanal

2-Methylbutyraldehyde

(2,4-dinitro-phenyl)-hydrazine