Ethylenebis(dicyclohexylphosphine oxide)

Base Information

• Chemical Name: Ethylenebis(dicyclohexylphosphine oxide)
• CAS No.: 16527-12-1
• Molecular Formula: C26H48O2P2
• Molecular Weight: 454.613
• DSSTox Substance ID: DTXSID001194357
• Nikkaji Number: J1.734.140E
• Mol file: 16527-12-1.mol

Synonyms:SCHEMBL1803741;DTXSID001194357;1,2-bis(dicyclohexylphosphinyl)ethane;Ethylenebis(dicyclohexylphosphine oxide);Phosphine oxide, 1,2-ethanediylbis[dicyclohexyl-;1,1'-(1,2-Ethanediyl)bis[1,1'-dicyclohexylphosphine oxide];Dicyclohexyl[2-(dicyclohexylphosphoryl)ethyl]phosphine oxide #;16527-12-1

Chemical Property of Ethylenebis(dicyclohexylphosphine oxide)

Chemical Property:

• XLogP3: 5.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 454.31295476
• Heavy Atom Count: 30
• Complexity: 509

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)P(=O)(CCP(=O)(C2CCCCC2)C3CCCCC3)C4CCCCC4

Technology Process of Ethylenebis(dicyclohexylphosphine oxide)

There total 3 articles about Ethylenebis(dicyclohexylphosphine oxide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,2-bis(diphenylphosphinoyl)ethane (4141-50-8) → C26H48O2P2 (16527-12-1)

Guidance literature:

With hydrogen; Ru-carbon; In methanol; at 150 ℃; for 72h; under 14710.2 Torr; var. cat. : PtO₂, 5percent Rh/C;

DOI:10.1246/cl.1984.1603

Reference yield: 93.3%

1,2-bis(dicyclohexylphosphinite)ethane → C26H48O2P2 (16527-12-1)

Guidance literature:

at 250 ℃; for 14h; Thermodynamic data;

DOI:10.1016/S0022-328X(01)01431-0

Reference yield:

1,2-bis-(dicyclohexylphosphino)ethane (23743-26-2) → C26H48O2P2 (16527-12-1)

Guidance literature:

With dihydrogen peroxide; In ethanol;

DOI:10.1016/S0022-328X(00)82529-2

upstream raw materials:

1,2-bis-(dicyclohexylphosphino)ethane

1,2-bis(diphenylphosphinoyl)ethane

Downstream raw materials:

(-)-(2R,3R)-2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(dicyclohexylphosphino)butane

(+)-(2S,3S)-2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(dicyclohexylphosphino)butane

(4R,5S)-4,5-Bis-[(dicyclohexylphosphanyl)-methyl]-2,2-dimethyl-[1,3]dioxolane

1,2-bis-(dicyclohexylphosphino)ethane