4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-methoxy-2-oxoethylidene)-3,3-dimethyl-7-oxo-, diphenylmethyl ester, (2S,5R,6Z)-

Base Information

Chemical Name:4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-methoxy-2-oxoethylidene)-3,3-dimethyl-7-oxo-, diphenylmethyl ester, (2S,5R,6Z)-
CAS No.:167028-45-7
Molecular Formula:C24H23NO5S
Molecular Weight:437.516
Hs Code.:
Mol file:167028-45-7.mol

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,
6-(2-methoxy-2-oxoethylidene)-3,3-dimethyl-7-oxo-, diphenylmethyl
ester, (2S,5R,6Z)-

Synonyms:

Suppliers and Price of 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-methoxy-2-oxoethylidene)-3,3-dimethyl-7-oxo-, diphenylmethyl ester, (2S,5R,6Z)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-methoxy-2-oxoethylidene)-3,3-dimethyl-7-oxo-, diphenylmethyl ester, (2S,5R,6Z)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-methoxy-2-oxoethylidene)-3,3-dimethyl-7-oxo-, diphenylmethyl ester, (2S,5R,6Z)-

There total 3 articles about 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-methoxy-2-oxoethylidene)-3,3-dimethyl-7-oxo-, diphenylmethyl ester, (2S,5R,6Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 129792-01-4
benzhydryl 6-oxopenicillinate

: 21204-67-1,2605-67-6
methyl (triphenylphosphoranylidene)acetate

: 167028-45-7
benzhydryl 6-(Z)-(1-methoxycarbonylmethylene)penicillanate

Guidance literature:: In dichloromethane; at -55 ℃; for 0.166667h;
DOI:10.1039/b409517k

Reference yield:

: 47547-28-4,78184-79-9
6-aminopenicillanic acid diphenylmethyl ester

: 167028-45-7
benzhydryl 6-(Z)-(1-methoxycarbonylmethylene)penicillanate

Guidance literature:: Multi-step reaction with 3 steps

1: isoamyl nitrite; TFA / CH₂Cl₂ / 0.5 h

2: 1.055 g / propylene oxide / rhodium(II) octanoate / benzene / 0.25 h

3: 67 percent / CH₂Cl₂ / 0.17 h / -55 °C

With trifluoroacetic acid; methyloxirane; isopentyl nitrite; rhodium(II) octanoate; In dichloromethane; benzene;
DOI:10.1039/b409517k

Reference yield:

: 65293-13-2
diphenylmethyl 6-diazopenicillanate

: 167028-45-7
benzhydryl 6-(Z)-(1-methoxycarbonylmethylene)penicillanate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.055 g / propylene oxide / rhodium(II) octanoate / benzene / 0.25 h

2: 67 percent / CH₂Cl₂ / 0.17 h / -55 °C

With methyloxirane; rhodium(II) octanoate; In dichloromethane; benzene;
DOI:10.1039/b409517k