Isothiochroman-4-one 2,2-dioxide

Base Information

• Chemical Name: Isothiochroman-4-one 2,2-dioxide
• CAS No.: 16723-58-3
• Molecular Formula: C9H8O3S
• Molecular Weight: 196.227
• Hs Code.: 2932999099
• Mol file: 16723-58-3.mol

Synonyms:Isothiochroman-4-one,2,2-dioxide;1H-2-Benzothiopyran-4(3H)-one,2,2-dioxide;

Chemical Property of Isothiochroman-4-one 2,2-dioxide

Chemical Property:

• Melting Point: 151-152 °C(Solv: acetic acid (64-19-7))
• Boiling Point: 457.3±34.0 °C(Predicted)
• PSA: 59.59000
• Density: 1.408±0.06 g/cm3(Predicted)
• LogP: 1.87850

Purity/Quality:

99% ^*data from raw suppliers

3,4-dihydro-1H-2lambda6-benzothiopyran-2,2,4-trione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Isothiochroman-4-one 2,2-dioxide

There total 12 articles about Isothiochroman-4-one 2,2-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

C11H11NO4S (1267655-01-5) → 3,4-dihydrobenzo[c]thiopyran-4-one 2,2-dioxide (16723-58-3)

Guidance literature:

With sodium alcoholate; In ethanol; at 80 ℃; for 10h;

DOI:10.1016/j.tetlet.2012.05.163

Reference yield: 93.0%

C12H13NO4S (1267798-71-9) → 3,4-dihydrobenzo[c]thiopyran-4-one 2,2-dioxide (16723-58-3)

Guidance literature:

With sodium alcoholate; In ethanol; at 80 ℃; for 10h;

DOI:10.1016/j.tetlet.2012.05.163

Reference yield: 79.0%

C11H11NO4S → 3,4-dihydrobenzo[c]thiopyran-4-one 2,2-dioxide (16723-58-3)

Guidance literature:

With sulfuric acid; for 2h; Reflux;

DOI:10.1016/j.tetlet.2012.05.163

upstream raw materials:

2-isothiochroman-4-one

S-benzylmercaptoacetic acid

C₁₁H₁₁NO₂S

C₁₂H₁₃NO₂S

Downstream raw materials:

C₁₅H₁₄N₂O₂S

Refernces

• 1、 Shyshkina, Olena O.,Tkachuk, Tetyana M.,Volovnenko, Tetiana A.,Volovenko, Yulian M.,Zubatyuk, Roman I.,Medviediev, Volodymyr V.,Shishkin, Oleg V.. "A novel synthesis and transformations of isothiochroman 2,2-dioxide". . p. 4296 - 4299. Retrieved 2012/09/25.
• 2、 Toshima, Kazunobu,Ohta, Kazumi,Ohtsuka, Atsuo,Matsumura, Shuichi,Nakata, Masaya. "Cycloaromatization and DNA Cleavage of Novel Enyne-allene Systems". . p. 1406 - 1407. Retrieved 2007/10/02.