benzyl N-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]carbamate

Base Information

Chemical Name:benzyl N-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]carbamate
CAS No.:168828-71-5
Molecular Formula:C₁₈H₁₉FN₂O₂S
Molecular Weight:346.425
Hs Code.:
DSSTox Substance ID:DTXSID601153822
Nikkaji Number:J1.494.337D
Mol file:168828-71-5.mol

Synonyms:168828-71-5;benzyl N-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]carbamate;Benzyl (3-fluoro-4-thiomorpholinophenyl)carbamate;benzyl N-(3-fluoro-4-thiomorpholin-4-ylphenyl)carbamate;C18H19FN2O2S;SCHEMBL8306382;IFTVWPQLBCYBPN-UHFFFAOYSA-N;DTXSID601153822;MFCD28016162;AKOS022193602;SS-4785;CS-0036889;W13552;Benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate;4-[2-fluoro-4-(benzyloxycarbonyl)aminophenyl]thiomorpholine;N-(3-Fluoro-4-thiomorpholinophenyl)carbamic acid benzyl ester;[3-Fluoro-4-(4-thiomorpholinyl)phenyl]carbamic acid phenylmethyl ester

Suppliers and Price of benzyl N-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate 97%
1g
$ 380.00

Ambeed
Benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate 97%
1g
$ 108.00

Ambeed
Benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate 97%
250mg
$ 53.00

Ambeed
Benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate 97%
5g
$ 326.00

Ambeed
Benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate 97%
100g
$ 3015.00

Ambeed
Benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate 97%
25g
$ 1077.00

AK Scientific
BenzylN-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]carbamate
1g
$ 582.80

AK Scientific
BenzylN-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]carbamate
250mg
$ 317.60

Total 8 raw suppliers

Chemical Property of benzyl N-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]carbamate

Chemical Property:

PSA：66.87000
LogP:4.26560
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:346.11512719
Heavy Atom Count:24
Complexity:401

Purity/Quality:

97% ^*data from raw suppliers

Benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CSCCN1C2=C(C=C(C=C2)NC(=O)OCC3=CC=CC=C3)F

Technology Process of benzyl N-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]carbamate

There total 5 articles about benzyl N-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: 237432-11-0
(3-fluoro-4-thiomorpholin-4-ylphenyl)amine

: 168828-71-5,1027134-68-4
[3-fluoro-4-(4-thiomorpholinyl)phenyl]carbamic acid, phenylmethyl ester

Guidance literature:: With sodium hydrogencarbonate; In tetrahydrofuran; at 0 ℃; for 1h;
DOI:10.1016/j.bmcl.2009.10.018

Reference yield:

: 369-34-6
3,4-difluoronitrobenzene

: 168828-71-5,1027134-68-4
[3-fluoro-4-(4-thiomorpholinyl)phenyl]carbamic acid, phenylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / N,N-diisopropylethylamine / acetonitrile / 1.) RT, 2.) reflux, 24 h

2: H₂ / W-2 Raney nickel / H₂O; tetrahydrofuran / 2 h / 2068.6 Torr

3: NaHCO₃ / H₂O; tetrahydrofuran / 0.5 h

With hydrogen; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; W-2 Raney nickel; In tetrahydrofuran; water; acetonitrile;
DOI:10.1021/jm950956y

Reference yield:

: 168828-70-4
(4-(2-fluoro-4-nitrophenyl)thiomorpholine)

: 168828-71-5,1027134-68-4
[3-fluoro-4-(4-thiomorpholinyl)phenyl]carbamic acid, phenylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / W-2 Raney nickel / H₂O; tetrahydrofuran / 2 h / 2068.6 Torr

2: NaHCO₃ / H₂O; tetrahydrofuran / 0.5 h

With hydrogen; sodium hydrogencarbonate; W-2 Raney nickel; In tetrahydrofuran; water;
DOI:10.1021/jm950956y