N-Desmethylterbinafine

Base Information

Chemical Name:N-Desmethylterbinafine
CAS No.:99473-11-7
Molecular Formula:C20H23 N
Molecular Weight:277.409
Hs Code.:2921499090
Nikkaji Number:J564.712F
Mol file:99473-11-7.mol

Synonyms:desmethylterbinafine;desmethylterbinafine hydrochloride, (E)-isomer;desmethylterbinafine, (E)-isomer

Suppliers and Price of N-Desmethylterbinafine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-Desmethylterbinafine
1mg
$ 460.00

TRC
N-DesmethylTerbinafine
1mg
$ 185.00

TRC
N-DesmethylTerbinafine
2mg
$ 350.00

Biosynth Carbosynth
N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-1-naphthalenemethanamine
2 mg
$ 1350.00

Biosynth Carbosynth
N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-1-naphthalenemethanamine
1 mg
$ 795.00

Biosynth Carbosynth
N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-1-naphthalenemethanamine
5 mg
$ 1950.00

American Custom Chemicals Corporation
N-DESMETHYL TERBINAFINE 95.00%
10MG
$ 1732.50

American Custom Chemicals Corporation
N-DESMETHYL TERBINAFINE 95.00%
1MG
$ 329.70

Total 10 raw suppliers

Chemical Property of N-Desmethylterbinafine

Chemical Property:

Vapor Pressure:9.71E-08mmHg at 25°C
Boiling Point:434.1°Cat760mmHg
Flash Point:228.5°C
PSA：12.03000
Density:1.011g/cm³
LogP:4.92600
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
XLogP3:5.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:277.183049738
Heavy Atom Count:21
Complexity:401

Purity/Quality:

99% ^*data from raw suppliers

N-Desmethylterbinafine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C#CC=CCNCC1=CC=CC2=CC=CC=C21
Isomeric SMILES:CC(C)(C)C#C/C=C/CNCC1=CC=CC2=CC=CC=C21

Technology Process of N-Desmethylterbinafine

There total 3 articles about N-Desmethylterbinafine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 917-92-0
3,3-Dimethylbut-1-yne

: (E)-3-chloro-N-(naphthalen-1-ylmethyl)prop-2-en-1-amine

: 99473-11-7,99450-97-2
Demethylterbinafine

Guidance literature:: With piperidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; at 20 ℃; for 48h;
DOI:10.1002/anie.201609480

Reference yield: 41.0%

: 118-31-0
(naphth-1-yl)methylamine

: 138139-82-9
trans-6,6-dimethylhept-2-en-4-yn-1-al

: 99473-11-7,99450-97-2
Demethylterbinafine

Guidance literature:: (naphth-1-yl)methylamine; trans-6,6-dimethylhept-2-en-4-yn-1-al; In methanol;

With sodium tetrahydroborate; In methanol;
DOI:10.1016/j.tetlet.2009.02.217