Cyclobutyl(oxo)diphenyl-lambda~5~-phosphane

Base Information

Chemical Name:Cyclobutyl(oxo)diphenyl-lambda~5~-phosphane
CAS No.:16958-47-7
Molecular Formula:C16H17OP
Molecular Weight:256.284
Hs Code.:
DSSTox Substance ID:DTXSID30544467
Wikidata:Q82421570
Mol file:16958-47-7.mol

Synonyms:16958-47-7;DTXSID30544467;Cyclobutyl(oxo)diphenyl-lambda~5~-phosphane

Suppliers and Price of Cyclobutyl(oxo)diphenyl-lambda~5~-phosphane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Cyclobutyl(oxo)diphenyl-lambda~5~-phosphane

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:256.101702159
Heavy Atom Count:18
Complexity:287

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Cyclobutyl(oxo)diphenyl-lambda~5~-phosphane

There total 7 articles about Cyclobutyl(oxo)diphenyl-lambda~5~-phosphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 4399-47-7
Bromocyclobutane

: 4559-70-0
Diphenylphosphine oxide

: 16958-47-7
cyclobutyldiphenylphosphine oxide

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; lithium methanolate; In 1-methyl-pyrrolidin-2-one; at 40 ℃; for 24h;
DOI:10.1039/c7ra02766d

Reference yield: 78.0%

: 3721-95-7
Cyclobutanecarboxylic acid

: 4559-70-0
Diphenylphosphine oxide

: 16958-47-7
cyclobutyldiphenylphosphine oxide

Guidance literature:: Cyclobutanecarboxylic acid; With dmap; dihydrogen peroxide; dicyclohexyl-carbodiimide; In dichloromethane; at 10 ℃; for 2h;

Diphenylphosphine oxide; With N,N,N,N,-tetramethylethylenediamine; copper(II) sulfate; In 1,2-dichloro-ethane; at 20 ℃;

Reference yield:

: 7333-63-3
4-bromobutylphosphonium bromide

: 16958-47-7
cyclobutyldiphenylphosphine oxide

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran; dimethylformamide

2: aq. NaOH

With sodium hydroxide; sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jo01272a014