1,2,4,5-Tetra(pyridin-4-yl)benzene

Base Information

• Chemical Name: 1,2,4,5-Tetra(pyridin-4-yl)benzene
• CAS No.: 170165-81-8
• Molecular Formula: C26H18N4
• Molecular Weight: 386.44800
• DSSTox Substance ID: DTXSID10570683
• Nikkaji Number: J1.790.158C
• Wikidata: Q82458210
• Mol file: 170165-81-8.mol

Synonyms:1,2,4,5-Tetra(pyridin-4-yl)benzene;170165-81-8;4-(2,4,5-tripyridin-4-ylphenyl)pyridine;YSWG120;SCHEMBL15389180;DTXSID10570683;1,2,4,5-tetra-(4-pyridyl)-benzene;1,2,4,5-tetra(pyridin-4-yl) benzene;BS-51914;CS-0110359;E78772;4,4',4'',4'''-(Benzene-1,2,4,5-tetrayl)tetrapyridine

Chemical Property of 1,2,4,5-Tetra(pyridin-4-yl)benzene

Chemical Property:

• Boiling Point: 529.1±45.0 °C(Predicted)
• PKA: 4.87±0.10(Predicted)
• PSA: 51.56000
• Density: 1.194±0.06 g/cm3(Predicted)
• LogP: 5.93460
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 386.153146591
• Heavy Atom Count: 30
• Complexity: 411

Purity/Quality:

≥99% ^*data from raw suppliers

1,2,4,5-Tetra(pyridin-4-yl)benzene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=CC=C1C2=CC(=C(C=C2C3=CC=NC=C3)C4=CC=NC=C4)C5=CC=NC=C5

Technology Process of 1,2,4,5-Tetra(pyridin-4-yl)benzene

There total 4 articles about 1,2,4,5-Tetra(pyridin-4-yl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1,2,4,5-tetrabromobenzene (636-28-2) + 4-pyridylboronic acid (1692-15-5) → 1,2,4,5-tetrakis (4-pyridyl) benzene (170165-81-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; for 36h; Schlenk technique; Inert atmosphere; Reflux;

DOI:10.1039/c2ce26520f

Reference yield: 65.0%

1,2,4,5-tetrabromobenzene (636-28-2) + 4-pyridineboronic acid pinacol ester (181219-01-2) → 4,4',4-(benzene-1,2,4-triyl)tripyridine + 1,2,4,5-tetrakis (4-pyridyl) benzene (170165-81-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; toluene; for 192h; Inert atmosphere; Reflux;

Reference yield: 58.0%

1,2,4,5-tetrabromobenzene (636-28-2) + 4-trimethylstannyl-pyridine (59020-06-3) → 1,2,4,5-tetrakis (4-pyridyl) benzene (170165-81-8)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; lithium chloride; In toluene; at 110 ℃;

DOI:10.1016/00404-0399(50)0983J-

upstream raw materials:

1,2,4,5-tetrabromobenzene

4-trimethylstannyl-pyridine

4-pyridylboronic acid

1,3-di(piperidin-4-yl)propane