Methanesulfonamide, N-phenyl-N-2-propenyl-

Base Information

• Chemical Name: Methanesulfonamide, N-phenyl-N-2-propenyl-
• CAS No.: 17240-55-0
• Molecular Formula: C10H13NO2S
• Molecular Weight: 211.285
• DSSTox Substance ID: DTXSID10454676
• Nikkaji Number: J2.557.394C
• Wikidata: Q82276342
• Mol file: 17240-55-0.mol

Synonyms:Methanesulfonamide, N-phenyl-N-2-propenyl-;DTXSID10454676;N-Allyl-N-phenylmethanesulfonamide;ADAL1242870;AKOS017085338;17240-55-0;N-PHENYL-N-(PROP-2-EN-1-YL)METHANESULFONAMIDE

Chemical Property of Methanesulfonamide, N-phenyl-N-2-propenyl-

Chemical Property:

• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 211.06669983
• Heavy Atom Count: 14
• Complexity: 273

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)N(CC=C)C1=CC=CC=C1

Technology Process of Methanesulfonamide, N-phenyl-N-2-propenyl-

There total 6 articles about Methanesulfonamide, N-phenyl-N-2-propenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-phenyl-N-(propa-1,2-dien-1-yl)methanesulfonamide (1369999-89-2) → N-phenyl-N-(prop-2-en-1-yl)methanesulfonamide (17240-55-0)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; formic acid; XPhos; In tetrahydrofuran; 1,2-dichloro-ethane; at 40 ℃; for 12h; regioselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.202103402

Reference yield: 66.0%

N-phenylmethanesulfonamide (1197-22-4) + allyl bromide (106-95-6) → N-phenyl-N-(prop-2-en-1-yl)methanesulfonamide (17240-55-0)

Guidance literature:

In ethanol; water; for 0.3h; Sonication;

DOI:10.1016/j.ultsonch.2021.105748

Reference yield:

aniline (62-53-3) → N-phenyl-N-(prop-2-en-1-yl)methanesulfonamide (17240-55-0)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 22 °C

2: potassium carbonate / acetone / Reflux

With potassium carbonate; triethylamine; In dichloromethane; acetone;

DOI:10.1021/acscatal.6b02586

upstream raw materials:

aniline

N-phenylmethanesulfonamide

allyl bromide

N-phenyl-N-(propa-1,2-dien-1-yl)methanesulfonamide

Downstream raw materials:

[5-ethoxythiocarbonylsulfanyl-6-(methanesulfonyl-phenyl-amino)-2-oxo-hexyl]-phosphonic acid diethyl ester

C₁₈H₂₇NO₆S₄

(E)-ethyl 4-((ethoxycarbonothioyl)thio)-5-(N-phenyl-methylsulfonamido)pent-2-enoate