(2S)-4-(Benzyloxy)-2-hydroxybutanoic acid

Base Information

Chemical Name:(2S)-4-(Benzyloxy)-2-hydroxybutanoic acid
CAS No.:172471-74-8
Molecular Formula:C11H14O4
Molecular Weight:210.23
Hs Code.:
DSSTox Substance ID:DTXSID90570969
Wikidata:Q82458545

Synonyms:172471-74-8;(2S)-4-(Benzyloxy)-2-hydroxybutanoic acid;SCHEMBL5217777;DTXSID90570969;4-O-benzyl-3-deoxy-l-glycero-tetronic acid

Suppliers and Price of (2S)-4-(Benzyloxy)-2-hydroxybutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (2S)-4-(Benzyloxy)-2-hydroxybutanoic acid

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:210.08920892
Heavy Atom Count:15
Complexity:187

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COCCC(C(=O)O)O
Isomeric SMILES:C1=CC=C(C=C1)COCC[C@@H](C(=O)O)O

Technology Process of (2S)-4-(Benzyloxy)-2-hydroxybutanoic acid

There total 6 articles about (2S)-4-(Benzyloxy)-2-hydroxybutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 256390-84-8
(S)-4-(hydroxymethyl)-2-phenyl-1,3-dioxane

: 172471-74-8
4-O-benzyl-L-glycero-tetronic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / CrO₃, Ac₂O, pyridine / CH₂Cl₂; dimethylformamide; 2-methyl-propan-2-ol / 16 h / Ambient temperature

2: 1.) BH₃*NMe₃, MS 4A, 2.) AlCl₃ / 1.) THF, r.t., 30 min, 2.) 0 deg C, 2 h

3: TFA / CH₂Cl₂ / 1 h / Ambient temperature

With pyridine; chromium(VI) oxide; aluminium trichloride; trimethylamine-borane; acetic anhydride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1080/07328309608005668

Reference yield:

: 616876-80-3
(S)-2-Phenyl-[1,3]dioxane-4-carboxylic acid (S)-2-phenyl-[1,3]dioxan-4-ylmethyl ester

: 172471-74-8
4-O-benzyl-L-glycero-tetronic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 48 percent / NaOMe / 0.5 h / 0 °C

2: 81 percent / CrO₃, Ac₂O, pyridine / CH₂Cl₂; dimethylformamide; 2-methyl-propan-2-ol / 16 h / Ambient temperature

3: 1.) BH₃*NMe₃, MS 4A, 2.) AlCl₃ / 1.) THF, r.t., 30 min, 2.) 0 deg C, 2 h

4: TFA / CH₂Cl₂ / 1 h / Ambient temperature

With pyridine; chromium(VI) oxide; aluminium trichloride; trimethylamine-borane; sodium methylate; acetic anhydride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1080/07328309608005668