2-Propenoic acid, 3-(3-methylphenyl)-, butyl ester, (2E)-

Base Information

• Chemical Name: 2-Propenoic acid, 3-(3-methylphenyl)-, butyl ester, (2E)-
• CAS No.: 173593-27-6
• Molecular Formula: C14H18O2
• Molecular Weight: 218.296
• Mol file: 173593-27-6.mol

Synonyms:

Chemical Property of 2-Propenoic acid, 3-(3-methylphenyl)-, butyl ester, (2E)-

Chemical Property:

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propenoic acid, 3-(3-methylphenyl)-, butyl ester, (2E)-

There total 10 articles about 2-Propenoic acid, 3-(3-methylphenyl)-, butyl ester, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + meta-bromotoluene (591-17-3) → (E)-3-(3-tolyl)acrylic acid n-butyl ester (173593-27-6)

Guidance literature:

With potassium carbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; 3-(2,6-diisopropylphenyl)-1-(2-diphenylphosphanylbenzyl)-3H-imidazol-1-ium chloride; In N,N-dimethyl acetamide; at 140 ℃; for 12h;

DOI:10.1016/j.tet.2004.10.049

Reference yield: 97.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + 3-Iodotoluene (625-95-6) → (E)-3-(3-tolyl)acrylic acid n-butyl ester (173593-27-6)

Guidance literature:

With dichloro bis(acetonitrile) palladium(II); potassium phosphate; N,N'-(1,2-ethanediylidene)bishexahydro-1H-azepin-1-amine; In N,N-dimethyl-formamide; at 80 ℃; for 6h;

DOI:10.1021/jo0610006

Reference yield: 91.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + sodium 3-methylbenzenesulfinate (15898-38-1) → (E)-3-(3-tolyl)acrylic acid n-butyl ester (173593-27-6)

Guidance literature:

With copper diacetate; palladium diacetate; In tetrahydrofuran; dimethyl sulfoxide; at 70 ℃; for 6h; stereoselective reaction;

DOI:10.1002/aoc.2970

upstream raw materials:

acrylic acid n-butyl ester

3-Iodotoluene

meta-bromotoluene

toluene

Refernces

• 1、 Du, Yijun,Qi, Chenze,Qin, Min,Shao, Linjun,Tao, Hongyu,Wang, Qingqing. "Encapsulating palladium nanoparticles inside ethylenediamine functionalized and crosslinked chlorinated poly(vinyl chloride) nanofibers as an efficient and stable heterogeneous catalyst for coupling reactions". . . Retrieved 2020/08/03.
• 2、 Cheng, Xu,Li, Guigen,Liu, Ruoyu,Liu, Xu,Qiu, Jiaxing. "Chemical-Reductant-Free Electrochemical Deuteration Reaction using Deuterium Oxide". supporting information. p. 13962 - 13967. Retrieved 2020/06/10.