Technology Process of 2-Fluorocyclooctan-1-one
There total 1 articles about 2-Fluorocyclooctan-1-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
xenon difluoride; hydrogen fluoride;
Yield given. Yields of byproduct given;
Ambient temperature;
DOI:10.1039/c39800000759
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 3 h / -78 °C
1.2: 1 h / -78 - 20 °C
2.1: potassium hexamethylsilazane / tetrahydrofuran; toluene / 1 h / -78 °C
2.2: 0.5 h / -78 - 20 °C
3.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 0 °C
With
potassium hexamethylsilazane; lithium diisopropyl amide;
In
tetrahydrofuran; n-heptane; ethylbenzene; toluene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 3 h / -78 °C
1.2: 1 h / -78 - 20 °C
2.1: potassium hexamethylsilazane / tetrahydrofuran; toluene / 1 h / -78 °C
2.2: 0.5 h / -78 - 20 °C
With
potassium hexamethylsilazane; lithium diisopropyl amide;
In
tetrahydrofuran; n-heptane; ethylbenzene; toluene;
