Phosphine oxide, diphenyl(1-phenyl-1,2-propadienyl)-

Base Information

• Chemical Name: Phosphine oxide, diphenyl(1-phenyl-1,2-propadienyl)-
• CAS No.: 17620-99-4
• Molecular Formula: C21H17OP
• Molecular Weight: 316.339
• DSSTox Substance ID: DTXSID80478607
• Nikkaji Number: J2.296.320A
• Mol file: 17620-99-4.mol

Synonyms:Phosphine oxide, diphenyl(1-phenyl-1,2-propadienyl)-;17620-99-4;DTXSID80478607

Chemical Property of Phosphine oxide, diphenyl(1-phenyl-1,2-propadienyl)-

Chemical Property:

• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 316.101702159
• Heavy Atom Count: 23
• Complexity: 448

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=C=C(C1=CC=CC=C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Phosphine oxide, diphenyl(1-phenyl-1,2-propadienyl)-

There total 7 articles about Phosphine oxide, diphenyl(1-phenyl-1,2-propadienyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-Phenyl-2-propyn-1-ol (1504-58-1) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → 1-phenylpropa-1,2-dien-1-yl diphenyl phosphine oxide (17620-99-4)

Guidance literature:

With triethylamine; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1021/jo8013462

Reference yield: 80.0%

methyl propargyl alcohol (764-01-2) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → 1-phenylpropa-1,2-dien-1-yl diphenyl phosphine oxide (17620-99-4)

Guidance literature:

With triethylamine; In dichloromethane; at -78 - 20 ℃; for 3h; Schlenk technique; Inert atmosphere;

DOI:10.1039/d0cc07770d

Reference yield: 74.0%

3-phenyl-2-propyn-1-yl methanesulfonate (82490-61-7) + Diphenylphosphine oxide (4559-70-0) → 1-phenylpropa-1,2-dien-1-yl diphenyl phosphine oxide (17620-99-4)

Guidance literature:

With 2,6-dimethylpyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 20 ℃; for 2h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.9b03645

upstream raw materials:

3-Phenyl-2-propyn-1-ol

chloro-diphenylphosphine

C₂₁H₁₇OP

3-phenyl-2-propyn-1-yl methanesulfonate

Downstream raw materials:

C₃₇H₃₉BOP₂

C₃₅H₃₅BOP₂

C₃₃H₃₁BOP₂

C₃₃H₄₃BOP₂