[2,2'-Bithiophene]-5-carboxaldehyde, 3,3'-dihexyl-

Base Information

• Chemical Name: [2,2'-Bithiophene]-5-carboxaldehyde, 3,3'-dihexyl-
• CAS No.: 177415-97-3
• Molecular Formula: C21H30OS2
• Molecular Weight: 362.601
• Mol file: 177415-97-3.mol

Synonyms:

Chemical Property of [2,2'-Bithiophene]-5-carboxaldehyde, 3,3'-dihexyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2,2'-Bithiophene]-5-carboxaldehyde, 3,3'-dihexyl-

There total 1 articles about [2,2'-Bithiophene]-5-carboxaldehyde, 3,3'-dihexyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-hexyl-2-bromothiophene (69249-61-2,125321-66-6) → 3,3'-dihexyl-[2,2'-bithiophene]-5-carbaldehyde (177415-97-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Mg; C₂H₄Br₂ / diethyl ether

1.2: 63 percent / Ni(dppp)Cl₂ / diethyl ether

2.1: 71 percent / POCl₃ / 1,2-dichloro-ethane

With C₂H₄Br₂; magnesium; trichlorophosphate; In diethyl ether; 1,2-dichloro-ethane;

DOI:10.1246/cl.2003.264

Reference yield:

3,3'-dihexyl-[2,2'-bithiophene]-5-carbaldehyde (177415-97-3) → C70H101N5O2S4

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium hydrogensulfate / toluene / 7 h / Reflux

2.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere

2.2: 13 h / -78 - 20 °C / Inert atmosphere

3.1: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutylammomium bromide / N,N-dimethyl-formamide; water / 12 h / 90 °C / Inert atmosphere

With potassium hydrogensulfate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; tetrabutylammomium bromide; potassium carbonate; In tetrahydrofuran; water; N,N-dimethyl-formamide; toluene;

DOI:10.1016/j.molstruc.2015.04.012

Reference yield:

3,3'-dihexyl-[2,2'-bithiophene]-5-carbaldehyde (177415-97-3) → (Z)-2-cyano-3-(5'-(4-(diphenylamino)phenyl)-3,3'-dihexyl-[2,2'-bithiophen]-5-yl)acrylic acid

Guidance literature:

Multi-step reaction with 4 steps

1.1: potassium hydrogensulfate / toluene / 7 h / Reflux

2.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere

2.2: 13 h / -78 - 20 °C / Inert atmosphere

3.1: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutylammomium bromide / N,N-dimethyl-formamide; water / 12 h / 90 °C / Inert atmosphere

4.1: acetic acid; ammonium acetate / 5 h / Inert atmosphere; Reflux

With potassium hydrogensulfate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; ammonium acetate; tetrabutylammomium bromide; potassium carbonate; acetic acid; In tetrahydrofuran; water; N,N-dimethyl-formamide; toluene;

DOI:10.1016/j.molstruc.2015.04.012

upstream raw materials:

3-hexyl-2-bromothiophene