4-Acetamido-3-methylbenzaldehyde

Base Information

Chemical Name:4-Acetamido-3-methylbenzaldehyde
CAS No.:177478-64-7
Molecular Formula:C10H11NO2
Molecular Weight:177.203
Hs Code.:
DSSTox Substance ID:DTXSID501288876

Synonyms:177478-64-7;N-(4-formyl-2-methylphenyl)acetamide;4-acetamido-3-methylbenzaldehyde;SCHEMBL7013927;RAFCKVCCTRBHKG-UHFFFAOYSA-N;DTXSID501288876;DB-109619

Suppliers and Price of 4-Acetamido-3-methylbenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Acetamido-3-methylbenzaldehyde

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:177.078978594
Heavy Atom Count:13
Complexity:203

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)C=O)NC(=O)C

Technology Process of 4-Acetamido-3-methylbenzaldehyde

There total 4 articles about 4-Acetamido-3-methylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 693224-73-6
N-[4-(hydroxymethyl)-2-methylphenyl]acetamide

: 177478-64-7
N-(4-formyl-2-methylphenyl)acetamide

Guidance literature:: With manganese(IV) oxide; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmc.2014.09.052

Reference yield:

: 88990-57-2
4-(Hydroxymethyl)-2-methylaniline

: 177478-64-7
N-(4-formyl-2-methylphenyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 82.2 percent / methanol / 2 h / 20 °C

2: 66.2 percent / triethylamine; SO₃*pyridine / dimethylsulfoxide / 2 h / 20 °C

With pyridine-SO₃ complex; triethylamine; In methanol; dimethyl sulfoxide;
DOI:10.1021/jm030326t

Reference yield:

: 2486-70-6
4-amino 3-methylbenzoic acid

: 177478-64-7
N-(4-formyl-2-methylphenyl)acetamide

Guidance literature:: Multi-step reaction with 4 steps

1: thionyl chloride / 12 h / 20 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 °C

3: triethylamine / dichloromethane / 2 h / 20 °C

4: manganese(IV) oxide / dichloromethane / 20 °C

With manganese(IV) oxide; lithium aluminium tetrahydride; thionyl chloride; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2014.09.052