Benzenamine, 2-(methylthio)-N-[(4-nitrophenyl)methylene]-

Base Information

• Chemical Name: Benzenamine, 2-(methylthio)-N-[(4-nitrophenyl)methylene]-
• CAS No.: 177903-57-0
• Molecular Formula: C14H12N2O2S
• Molecular Weight: 272.327
• Mol file: 177903-57-0.mol

Synonyms:

Chemical Property of Benzenamine, 2-(methylthio)-N-[(4-nitrophenyl)methylene]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenamine, 2-(methylthio)-N-[(4-nitrophenyl)methylene]-

There total 1 articles about Benzenamine, 2-(methylthio)-N-[(4-nitrophenyl)methylene]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(Methylthio)aniline (2987-53-3) + 4-nitrobenzaldehdye (555-16-8) → 2-methylthio-N-(4-nitrobenzylidene)aniline (177903-57-0)

Guidance literature:

With magnesium sulfate; In dichloromethane; at 22 ℃; for 20h; Sealed tube; Inert atmosphere;

DOI:10.1016/j.tetlet.2015.04.006

Reference yield: 70.0%

ammonium hexafluorophosphate + [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 (52462-29-0) + 2-methylthio-N-(4-nitrobenzylidene)aniline (177903-57-0) → [RuCl(η6-p-cymene)(MeS-C6H4-2-N=CH-C6H4-4-NO2)][PF6] (879690-52-5)

Guidance literature:

In methanol; Ru-contg. compd. (0.163 mmol) was added to a soln. of a ligand (0.325 mmol) in MeOH; stirring at room temp. for 4 h; excess of NH4PF6 (0.356 mmol) was added; solid was collected by vac. filtration, washed once with cold methanol, and dried in vac.; elem. anal.;

DOI:10.1016/j.ica.2005.06.017

Reference yield: 39.0%

trimethyl-(5-methyl-furan-2-yloxy)-silane (61550-05-8) + 2-methylthio-N-(4-nitrobenzylidene)aniline (177903-57-0) → (5R)-5-methyl-5-(((2-(methylthio)phenyl)amino)(4-nitrophenyl)methyl)furan-2(5H)-one + C19H18N2O4S

Guidance literature:

2-methylthio-N-(4-nitrobenzylidene)aniline; With C₃₂H₃₃N₂O₂P; silver(I) acetate; In tetrahydrofuran; isopropyl alcohol; for 0.166667h; Inert atmosphere; Darkness;

trimethyl-(5-methyl-furan-2-yloxy)-silane; In tetrahydrofuran; isopropyl alcohol; at -78 ℃; for 18h; Inert atmosphere; Darkness;

With acetic acid; In tetrahydrofuran; methanol; isopropyl alcohol; at -78 ℃; for 3h; enantioselective reaction; Inert atmosphere; Darkness;

DOI:10.1016/j.tetlet.2015.04.006

upstream raw materials:

2-(Methylthio)aniline

4-nitrobenzaldehdye

Downstream raw materials:

Hg(C₁₄H₁₂N₂O₂S)Cl₂

[(η3-2-methylallyl)Pd(η2-S,N-2-MeSC6H4N=CHC6H4NO2-4)]BF4

[RuCl(η6-p-cymene)(MeS-C6H4-2-N=CH-C6H4-4-NO2)][PF6]