3-CHLORO-2-NITROPHENOL

Base Information

• Chemical Name: 3-CHLORO-2-NITROPHENOL
• CAS No.: 17802-02-7
• Molecular Formula: C6H4ClNO3
• Molecular Weight: 173.556
• Hs Code.: 2908999090
• Mol file: 17802-02-7.mol

Synonyms:3-Chloro-2-nitrobenzyl alcohol;2-nitro-3-chlorophenol;Benzenemethanol,3-chloro-2-nitro;3-Chlor-2-nitro-1-hydroxy-benzol;3-Chlor-2-nitrophenol;3-chloro-2-nitro-phenol;3-chloro-2-nitrobenzenemethanol;

Chemical Property of 3-CHLORO-2-NITROPHENOL

Chemical Property:

• Vapor Pressure: 0.013mmHg at 25°C
• Melting Point: 37.5 °C
• Boiling Point: 250.795oC at 760 mmHg
• PKA: 4.45±0.10(Predicted)
• Flash Point: 105.478oC
• PSA: 66.05000
• Density: 1.554g/cm3
• LogP: 2.47700
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%Min ^*data from raw suppliers

3-Chloro-2-nitrophenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-CHLORO-2-NITROPHENOL

There total 7 articles about 3-CHLORO-2-NITROPHENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-chloro-3-fluoro-2-nitrobenzene (64182-61-2) → 2-nitro-3-chlorophenol (17802-02-7)

Guidance literature:

With lithium hydroxide; dihydrogen peroxide; In tetrahydrofuran; water; at 60 ℃; for 72h;

Reference yield: 33.0%

3-monochlorophenol (108-43-0) → 2-nitro-3-chlorophenol (17802-02-7)

Guidance literature:

With ammonium nickel(II) sulfate hexahydrate; nitric acid; In dichloromethane; at 20 ℃; for 3h; Cooling with ice;

Reference yield:

2-Chloronitrobenzene (88-73-3) → 3-chloro-4-nitrophenol (491-11-2) + 2-nitro-3-chlorophenol (17802-02-7) + 2-hydroxynitrobenzene (88-75-5,78813-12-4)

Guidance literature:

With potassium hydroxide; oxygen; In ammonia; at -33 ℃;

upstream raw materials:

3-monochlorophenol

2-Chloronitrobenzene

sulfuric acid

1-chloro-3-fluoro-2-nitrobenzene

Downstream raw materials:

C₃₀H₃₆N₂O₄

C₂₉H₃₄N₂O₄

6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine

1-chloro-3-ethoxy-2-nitrobenzene

Refernces

• 1、 -. "CONDENSED HETEROCYCLIC COMPOUND". Paragraph 0381-0383. . Retrieved 2017/11/08.
• 2、 -. "PYRAZOLE COMPOUNDS". Page/Page column 29. . Retrieved 2010/04/30.