4-Methyl-2,6-bis(trimethylsilyl)phenol

Base Information

Chemical Name:4-Methyl-2,6-bis(trimethylsilyl)phenol
CAS No.:18033-63-1
Molecular Formula:C13H24OSi2
Molecular Weight:252.504
Hs Code.:
DSSTox Substance ID:DTXSID90569616
Nikkaji Number:J492.429K
Wikidata:Q82456790
Mol file:18033-63-1.mol

Synonyms:4-Methyl-2,6-bis(trimethylsilyl)phenol;18033-63-1;DTXSID90569616

Suppliers and Price of 4-Methyl-2,6-bis(trimethylsilyl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-Methyl-2,6-bis(trimethylsilyl)phenol

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:252.13656845
Heavy Atom Count:16
Complexity:215

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)[Si](C)(C)C)O)[Si](C)(C)C

Technology Process of 4-Methyl-2,6-bis(trimethylsilyl)phenol

There total 2 articles about 4-Methyl-2,6-bis(trimethylsilyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1313182-64-7
trimethylsilyl 2-bromo-4-methyl-6-(trimethylsilyl)phenyl ether

: 18033-63-1
4-methyl-2,6-bis(trimethylsilyl)phenol

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1.25h; Inert atmosphere;
DOI:10.1002/anie.201100360

Reference yield:

: 154345-34-3
2-bromo-4-methyl-6-(trimethylsilyl)phenol

: 18033-63-1
4-methyl-2,6-bis(trimethylsilyl)phenol

Guidance literature:: Multi-step reaction with 2 steps

1: 1H-imidazole / tetrahydrofuran / 2.5 h / 20 °C / Inert atmosphere

2: n-butyllithium / tetrahydrofuran; hexane / 1.25 h / -78 - 20 °C / Inert atmosphere

With 1H-imidazole; n-butyllithium; In tetrahydrofuran; hexane;
DOI:10.1002/anie.201100360

Reference yield: 74.0%

: 358-23-6
trifluoromethylsulfonic anhydride

: 18033-63-1
4-methyl-2,6-bis(trimethylsilyl)phenol

: 97391-19-0
4-methyl-2,6-bis(trimethylsilyl)phenyl trifluoromethanesulfonate

Guidance literature:: With n-butyllithium; In tetrahydrofuran; diethyl ether; hexane; at -78 - 20 ℃; for 1.08333h; Inert atmosphere;
DOI:10.1002/anie.201100360