1,4-BIS(PHENYLMETHYL)-4-PIPERIDINECARBOXYLIC ACID

Base Information

• Chemical Name: 1,4-BIS(PHENYLMETHYL)-4-PIPERIDINECARBOXYLIC ACID
• CAS No.: 181641-74-7
• Molecular Formula: C20H23NO2
• Molecular Weight: 309.40200
• Mol file: 181641-74-7.mol

Synonyms:1,4-Bis-benzyl-4-piperidinecarboxylicacid;

Chemical Property of 1,4-BIS(PHENYLMETHYL)-4-PIPERIDINECARBOXYLIC ACID

Chemical Property:

• PSA: 40.54000
• LogP: 3.53400

Purity/Quality:

99% ^*data from raw suppliers

1,4-Bis-benzyl-4-piperidinecarboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,4-BIS(PHENYLMETHYL)-4-PIPERIDINECARBOXYLIC ACID

There total 2 articles about 1,4-BIS(PHENYLMETHYL)-4-PIPERIDINECARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

BrH*C22H27NO2 → 1,4-Dibenzyl-4-carboxypiperidine (181641-74-7)

Guidance literature:

With sodium hydroxide; In ethanol; water; Reflux;

DOI:10.1016/j.bmcl.2009.01.012

Reference yield:

→ 1,4-Dibenzyl-4-carboxypiperidine (181641-74-7)

Guidance literature:

Reference yield: 56.0%

1,4-Dibenzyl-4-carboxypiperidine (181641-74-7) → C20H24N2O (1143582-75-5)

Guidance literature:

With dmap; ammonia; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; at 20 ℃;

DOI:10.1016/j.bmcl.2009.01.012

Downstream raw materials:

C₂₀H₂₄N₂O