(3S,5R)-3,8-Dihydroxy-κ,χ-caroten-6-one

Base Information

• Chemical Name: (3S,5R)-3,8-Dihydroxy-κ,χ-caroten-6-one
• CAS No.: 55906-76-8
• Molecular Formula: C₄₀H₅₂O₃
• Molecular Weight: 580.851
• Mol file: 55906-76-8.mol

Synonyms:Trikentriorhodin;(2Z,4E,6E,8E,10E,12E,14E,16E,18E)-3-Hydroxy-1-((1R,4S)-4-hydroxy-1,2,2-trimethyl-cyclopentyl)-4,8,13,17-tetramethyl-19-(2,3,4-trimethyl-phenyl)-nonadeca-2,4,6,8,10,12,14,16,18-nonaen-1-one;

Chemical Property of (3S,5R)-3,8-Dihydroxy-κ,χ-caroten-6-one

Chemical Property:

• Melting Point: 255 - 260 °C (diethyl ether)
• PSA: 57.53000
• LogP: 10.27700

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3S,5R)-3,8-Dihydroxy-κ,χ-caroten-6-one

There total 10 articles about (3S,5R)-3,8-Dihydroxy-κ,χ-caroten-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3S,5R)-8-hydroxy-3-trimethylsilyloxy-κ,χ-caroten-6-one (65252-71-3) → trikentriorhodin (55906-76-8)

Guidance literature:

With hydrogenchloride; In methanol; at 20 ℃; Yield given; Heating;

Reference yield:

(2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial (5056-17-7) → trikentriorhodin (55906-76-8)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium hydroxyde / propan-2-ol; H₂O / 3 h / 20 °C

2: potassium hydroxyde / H₂O; propan-2-ol / 3 h / 20 °C

3: lithamide / tetrahydrofuran / Heating

4: 2 M hydrochloric acid / methanol / 20 °C / Heating

With hydrogenchloride; potassium hydroxide; lithium amide; In tetrahydrofuran; methanol; water; isopropyl alcohol;

Reference yield:

methyl 12-oxo-2,6,11-trimethyldodeca-2,4,6,8,10-pentaenoate (65243-76-7) → trikentriorhodin (55906-76-8)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium hydroxyde / H₂O; propan-2-ol / 3 h / 20 °C

2: lithamide / tetrahydrofuran / Heating

3: 2 M hydrochloric acid / methanol / 20 °C / Heating

With hydrogenchloride; potassium hydroxide; lithium amide; In tetrahydrofuran; methanol; water; isopropyl alcohol;

upstream raw materials:

(3S,5R)-8-hydroxy-3-trimethylsilyloxy-κ,χ-caroten-6-one

(2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial

methyl 12-oxo-2,6,11-trimethyldodeca-2,4,6,8,10-pentaenoate

3-methyl-5-(2,3,4-trimethylphenyl)penta-2,4-dien-1-yltriphenylphosphonium bromide