1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 3-bromo-4-(1-methylethoxy)-

Base Information

Chemical Name:1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 3-bromo-4-(1-methylethoxy)-
CAS No.:183274-50-2
Molecular Formula:C8H10BrN5O
Molecular Weight:272.10200
Hs Code.:2933599590
DSSTox Substance ID:DTXSID60415914
Nikkaji Number:J1.925.442I
Wikidata:Q82224990
Mol file:183274-50-2.mol

Synonyms:183274-50-2;1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 3-bromo-4-(1-methylethoxy)-;3-bromo-4-isopropoxy-1h-pyrazolo[3,4-d]pyrimidin-6-amine;3-bromo-4-propan-2-yloxy-2H-pyrazolo[3,4-d]pyrimidin-6-amine;3-Bromo-4-(propan-2-yloxy)-1H-pyrazolo[3,4-d]pyrimidin-6-amine;DTXSID60415914;RYSAHLTXAATJRZ-UHFFFAOYSA-N;F18334;A880837;3-Bromo-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidine-6-amine;1h-pyrazolo[3,4-d]pyrimidin-6-amine,3-bromo-4-(1-methylethoxy)-;3-Bromo-4-(1-methylethoxy)-1H-pyrazolo[3,4-d]pyrimidin-6-amine;InChI=1/C8H10BrN5O/c1-3(2)15-7-4-5(9)13-14-6(4)11-8(10)12-7/h3H,1-2H3,(H3,10,11,12,13,14

Suppliers and Price of 1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 3-bromo-4-(1-methylethoxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Bromo-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine 95+%
1g
$ 480.00

Chemenu
3-Bromo-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine 95%
1g
$ 449.00

Alichem
3-Bromo-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine
1g
$ 499.20

Total 9 raw suppliers

Chemical Property of 1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 3-bromo-4-(1-methylethoxy)-

Chemical Property:

PSA：90.44000
LogP:1.41490
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:271.00687
Heavy Atom Count:15
Complexity:229

Purity/Quality:

97% ^*data from raw suppliers

3-Bromo-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)OC1=NC(=NC2=NNC(=C21)Br)N

Technology Process of 1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 3-bromo-4-(1-methylethoxy)-

There total 2 articles about 1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 3-bromo-4-(1-methylethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 183274-49-9
4-Isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-ylamine

: 183274-50-2
3-bromo-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine

Guidance literature:: With N-Bromosuccinimide;

Reference yield:

: 100644-65-3
4-chloro-1H-pyrazolo[3,4-d]pyrimidine-6-amine

: 183274-50-2
3-bromo-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / i-PrONa / 1 h / Heating

2: 78 percent / NBS / 1,2-dichloro-ethane / 1.5 h / Heating

With N-Bromosuccinimide; sodium isopropylate; In 1,2-dichloro-ethane;
DOI:10.1055/s-1998-4483

Reference yield: 60.0%

: 97614-44-3
2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide

: 183274-50-2
3-bromo-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine

: 3-bromo-1-(5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine

: 577992-09-7
3-bromo-2-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-β-D-arabinofuranosyl)-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine

: 577990-95-5
3-bromo-1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-β-D-arabinofuranosyl)-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine

Guidance literature:: 3-bromo-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine; With potassium hydroxide; In acetonitrile; at 20 ℃; for 0.25h;

2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide; In acetonitrile; for 0.333333h;
DOI:10.1021/jo030051p