1-(Phenylethynyl)-3,4-dihydronaphthalene-2-carbaldehyde

Base Information

Chemical Name:1-(Phenylethynyl)-3,4-dihydronaphthalene-2-carbaldehyde
CAS No.:183859-96-3
Molecular Formula:C19H14O
Molecular Weight:258.32
Hs Code.:
DSSTox Substance ID:DTXSID80570478
Nikkaji Number:J770.490I
Wikidata:Q82457945
Mol file:183859-96-3.mol

Synonyms:1-(Phenylethynyl)-3,4-dihydronaphthalene-2-carbaldehyde;183859-96-3;DTXSID80570478

Suppliers and Price of 1-(Phenylethynyl)-3,4-dihydronaphthalene-2-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(Phenylethynyl)-3,4-dihydronaphthalene-2-carbaldehyde

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:258.104465066
Heavy Atom Count:20
Complexity:453

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=C(C2=CC=CC=C21)C#CC3=CC=CC=C3)C=O

Technology Process of 1-(Phenylethynyl)-3,4-dihydronaphthalene-2-carbaldehyde

There total 4 articles about 1-(Phenylethynyl)-3,4-dihydronaphthalene-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 3262-03-1
1-chloro-2-formyl-3,4-dihydronaphthalene

: 536-74-3
phenylacetylene

: 183859-96-3
1-phenylethynyl-3,4-dihydronaphthalene-2-carboxaldehyde

Guidance literature:: With copper(l) iodide; triethylamine; triphenylphosphine; palladium dichloride; at 80 ℃; for 18h;
DOI:10.1055/s-2003-38081

Reference yield: 89.0%

: 117582-62-4
1-bromo-2-formyl-3,4-dihydronaphthalene

: 536-74-3
phenylacetylene

: 183859-96-3
1-phenylethynyl-3,4-dihydronaphthalene-2-carboxaldehyde

Guidance literature:: With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; at 50 ℃; for 0.833333h;
DOI:10.1002/jlac.199619961120

Reference yield:

: 529-34-0
3,4-dihydronaphthalene-1(2H)-one

: 183859-96-3
1-phenylethynyl-3,4-dihydronaphthalene-2-carboxaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: phosphorus tribromide / chloroform / 0 - 20 °C / Inert atmosphere

2.1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / N,N-dimethyl-formamide / 0.17 h / 20 °C / Inert atmosphere

2.2: Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; phosphorus tribromide; In chloroform; N,N-dimethyl-formamide; 1.1: |Vilsmeier-Haack Formylation / 2.1: |Suzuki Coupling / 2.2: |Suzuki Coupling;
DOI:10.1039/c4ra02581d