14-Methylcholesterol

Base Information

Chemical Name:14-Methylcholesterol
CAS No.:115090-73-8
Molecular Formula:C₂₈H₄₈O
Molecular Weight:400.689
Hs Code.:
DSSTox Substance ID:DTXSID20921622
Mol file:115090-73-8.mol

Synonyms:14-methylcholesterol

Suppliers and Price of 14-Methylcholesterol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 14-Methylcholesterol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:484.223°C at 760 mmHg
Flash Point:212.812°C
PSA：20.23000
Density:0.984g/cm³
LogP:7.77880
XLogP3:8.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:400.370516150
Heavy Atom Count:29
Complexity:634

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CCCC(C)C1CCC2(C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C
Isomeric SMILES:C[C@H](CCCC(C)C)[C@H]1CCC2([C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C

Technology Process of 14-Methylcholesterol

There total 3 articles about 14-Methylcholesterol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 115058-84-9
4-oxa-3,14α-dimethylcholestan-3ξ,5ξ-diol

: 115090-73-8
14α-methylcholesterol

Guidance literature:: Multi-step reaction with 2 steps

1: 10percent NaOH / methanol / 2 h / Heating

2: 1.) isopropenyl acetate, p-toluenesulfonic acid; 2.) NaBH₄ / 1.) benzene, reflux, 5 h; 2.) tetrahydrofuran, methanol, reflux, 1 h

With sodium hydroxide; sodium tetrahydroborate; Isopropenyl acetate; toluene-4-sulfonic acid; In methanol;
DOI:10.1248/cpb.35.3467

Reference yield:

: 21857-91-0
(8R,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13,14-trimethyl-1,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-2H-4-oxa-cyclopenta[a]phenanthren-3-one

: 115090-73-8
14α-methylcholesterol

Guidance literature:: Multi-step reaction with 3 steps

1: diethyl ether; benzene / 0.5 h

2: 10percent NaOH / methanol / 2 h / Heating

3: 1.) isopropenyl acetate, p-toluenesulfonic acid; 2.) NaBH₄ / 1.) benzene, reflux, 5 h; 2.) tetrahydrofuran, methanol, reflux, 1 h

With sodium hydroxide; sodium tetrahydroborate; Isopropenyl acetate; toluene-4-sulfonic acid; In methanol; diethyl ether; benzene;
DOI:10.1248/cpb.35.3467

Reference yield:

: 21857-92-1
14-methyl-cholest-4-en-3-one

: 115058-86-1
14α-methylcholest-5-en-3α-ol

: 115090-73-8
14α-methylcholesterol

Guidance literature:: With sodium tetrahydroborate; Isopropenyl acetate; toluene-4-sulfonic acid; Yield given. Multistep reaction. Yields of byproduct given; 1.) benzene, reflux, 5 h; 2.) tetrahydrofuran, methanol, reflux, 1 h;
DOI:10.1248/cpb.35.3467