alpha-Ethyl-p-hydroxy-hydrocinnamic acid

Base Information

Chemical Name:alpha-Ethyl-p-hydroxy-hydrocinnamic acid
CAS No.:17086-23-6
Molecular Formula:C11H14 O3
Molecular Weight:194.2271
Hs Code.:
NSC Number:31643
UNII:0L557IU5L4
Wikidata:Q27236925
Mol file:17086-23-6.mol

Synonyms:UNII-0L557IU5L4;alpha-Ethyl-p-hydroxy-hydrocinnamic acid;17086-23-6;0L557IU5L4;alpha-(4-Hydroxybenzyl)butyric acid;NSC 31643;Hydrocinnamic acid, alpha-ethyl-p-hydroxy-;Benzenepropanoic acid, alpha-ethyl-4-hydroxy-;Hydrocinnamic acid, .alpha.-ethyl-p-hydroxy-;Benzenepropanoic acid, .alpha.-ethyl-4-hydroxy-;NSC-31643;.alpha.-(4-Hydroxybenzyl)butyric acid;NSC31643;SCHEMBL6379983;AKOS017532455;.ALPHA.-ETHYL-P-HYDROXYHYDROCINNAMIC ACID;.ALPHA.-ETHYL-P-HYDROXY-HYDROCINNAMIC ACID;Q27236925

Suppliers and Price of alpha-Ethyl-p-hydroxy-hydrocinnamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of alpha-Ethyl-p-hydroxy-hydrocinnamic acid

Chemical Property:

Vapor Pressure:6.86E-06mmHg at 25°C
Boiling Point:362.5°Cat760mmHg
Flash Point:187.2°C
Density:1.175g/cm³
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:194.094294304
Heavy Atom Count:14
Complexity:183

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(CC1=CC=C(C=C1)O)C(=O)O

Technology Process of alpha-Ethyl-p-hydroxy-hydrocinnamic acid

There total 4 articles about alpha-Ethyl-p-hydroxy-hydrocinnamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: N-(3,4-difluoro-2-(1H-pyrazol-1-yl)phenyl)-2-(4-methoxybenzyl)butanamide

: 17086-23-6
2-(4-hydroxybenzyl)butanoic acid

Guidance literature:: With hydrogenchloride; In water; at 110 ℃; for 20h;
DOI:10.1021/acs.joc.9b01276

Reference yield:

: 28166-40-7
α-Ethyl-p-hydroxyzimtsaeure

: 17086-23-6
2-(4-hydroxybenzyl)butanoic acid

Guidance literature:: With sodium hydroxide; aluminum nickel;
DOI:10.1021/ja01162a077

Reference yield:

: 5856-79-1,57526-28-0
iso-butyl chloroformate

: 17086-23-6
2-(4-hydroxybenzyl)butanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 2.17 h / 0 - 20 °C

2: palladium diacetate; copper diacetate; silver orthophosphate / para-xylene; N,N-dimethyl-formamide / 16 h / 130 °C / Sealed tube

3: hydrogenchloride / water / 20 h / 110 °C

With hydrogenchloride; silver orthophosphate; copper diacetate; palladium diacetate; triethylamine; In dichloromethane; para-xylene; water; N,N-dimethyl-formamide;
DOI:10.1021/acs.joc.9b01276