Alanine, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-2-methylalanyl-L-alanyl-2-meth ylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methyl-, phenylmethyl ester

Base Information

Chemical Name:Alanine, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-2-methylalanyl-L-alanyl-2-meth ylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methyl-, phenylmethyl ester
CAS No.:184099-95-4
Molecular Formula:C40H64N8O11
Molecular Weight:832.995
Hs Code.:

Alanine,
N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-2-methylalanyl-L-alanyl-2-meth
ylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methyl-, phenylmethyl ester

Synonyms:

Suppliers and Price of Alanine, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-2-methylalanyl-L-alanyl-2-meth ylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methyl-, phenylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Alanine, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-2-methylalanyl-L-alanyl-2-meth ylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methyl-, phenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Alanine, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-2-methylalanyl-L-alanyl-2-meth ylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methyl-, phenylmethyl ester

There total 9 articles about Alanine, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-2-methylalanyl-L-alanyl-2-meth ylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methyl-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 184099-93-2
Boc-(Ala-Aib)2-OH

: 2-{(S)-2-[2-((S)-2-Amino-propionylamino)-2-methyl-propionylamino]-propionylamino}-2-methyl-propionic acid benzyl ester; hydrochloride

: 184099-95-4
2-((S)-2-{2-[(S)-2-(2-{(S)-2-[2-((S)-2-tert-Butoxycarbonylamino-propionylamino)-2-methyl-propionylamino]-propionylamino}-2-methyl-propionylamino)-propionylamino]-2-methyl-propionylamino}-propionylamino)-2-methyl-propionic acid benzyl ester

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide; for 36h; Ambient temperature;

Reference yield:

: 79118-33-5
Boc-Ala-Aib-OBzl

: 184099-95-4
2-((S)-2-{2-[(S)-2-(2-{(S)-2-[2-((S)-2-tert-Butoxycarbonylamino-propionylamino)-2-methyl-propionylamino]-propionylamino}-2-methyl-propionylamino)-propionylamino]-2-methyl-propionylamino}-propionylamino)-2-methyl-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: HCl / dioxane

2: 39 percent / N-methylmorpholine, BtOH, EDC / dimethylformamide / 36 h / Ambient temperature

3: 99 percent / H₂ / Pd/C / methanol / 760 Torr

4: 79 percent / N-methylmorpholine, BtOH, EDC / dimethylformamide / 36 h / Ambient temperature

With 4-methyl-morpholine; hydrogenchloride; hydrogen; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium on activated charcoal; In 1,4-dioxane; methanol; N,N-dimethyl-formamide;

Reference yield:

: 72095-04-6
Boc-Ala-Aib-OH

: 184099-95-4
2-((S)-2-{2-[(S)-2-(2-{(S)-2-[2-((S)-2-tert-Butoxycarbonylamino-propionylamino)-2-methyl-propionylamino]-propionylamino}-2-methyl-propionylamino)-propionylamino]-2-methyl-propionylamino}-propionylamino)-2-methyl-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 39 percent / N-methylmorpholine, BtOH, EDC / dimethylformamide / 36 h / Ambient temperature

2: 99 percent / H₂ / Pd/C / methanol / 760 Torr

3: 79 percent / N-methylmorpholine, BtOH, EDC / dimethylformamide / 36 h / Ambient temperature

With 4-methyl-morpholine; hydrogen; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;