Deoxyvincamine

Base Information

Chemical Name:Deoxyvincamine
CAS No.:21019-23-8
Molecular Formula:C21H26N2O2
Molecular Weight:338.4433
Hs Code.:
DSSTox Substance ID:DTXSID70943319
Nikkaji Number:J103.738B
Wikipedia:Desoxyvincaminol
Wikidata:Q15088333

Synonyms:Deoxyvincamine;Desoxyvincamine;Vincamine, deoxy-;Vincamine, 14-deoxy-;21019-23-8;Methyl (3-alpha,14-alpha,16-alpha)-14,15-dihydroeburnamenine-14-carboxylate;Eburnamenine-14-carboxylic acid, 14,15-dihydro-, methyl ester, (3-alpha,14-alpha,16-alpha)-;Desoxyvincaminol;DTXSID70943319;LS-63710;Methyl 14,15-dihydroeburnamenine-14-carboxylate;Q15088333;methyl (15S,17R,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate

Suppliers and Price of Deoxyvincamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Deoxyvincamine

Chemical Property:

Vapor Pressure:1.29E-09mmHg at 25°C
Boiling Point:486.5°Cat760mmHg
Flash Point:248°C
Density:1.31g/cm³
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:338.199428076
Heavy Atom Count:25
Complexity:552

Purity/Quality:: >95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)C(=O)OC
Isomeric SMILES:CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4[C@H](C2)C(=O)OC

Technology Process of Deoxyvincamine

There total 26 articles about Deoxyvincamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 4880-92-6
apovincamine

: 21019-23-8
(3S,16S,14R)-14-deoxyvincamine

Guidance literature:: In palladium on charcoal catalyst; water; acetic acid;

Reference yield: 27.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 59639-59-7,61826-71-9,61848-76-8,62474-77-5,70614-21-0,123806-79-1,123806-80-4,123806-81-5
(+/-)-eburnane-16β-carbonitrile

: 59656-84-7,70614-84-5,71075-45-1,123806-82-6,123806-83-7,123806-84-8
(10R,11aR,11bR)-11a-Ethyl-2,3,4,5,10,11,11a,11b-octahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid amide

: 21019-23-8,21019-24-9,57130-30-0,59684-93-4,68779-69-1,68779-71-5,70614-18-5,80735-18-8,96245-03-3,96245-04-4,105500-11-6,105500-21-8,105561-05-5,105561-07-7
deoxyvincamine

Guidance literature:: With hydrogenchloride; Yield given. Multistep reaction; 1. reflux, 8 h; 2. ether;

Reference yield:

: 68796-67-8
1-propyl-4,9-dihydro-3H-pyrido<3,4-b>indole

: 21019-23-8,21019-24-9,57130-30-0,59684-93-4,68779-69-1,68779-71-5,70614-18-5,80735-18-8,96245-03-3,96245-04-4,105500-11-6,105500-21-8,105561-05-5,105561-07-7
deoxyvincamine

Guidance literature:: Multi-step reaction with 6 steps

1: 75 percent / 1.) i-Pr₂NEt, 2.) LiClO₄ / acetonitrile / 8 h / Heating

2: 5.4 g / 1.) i-Pr₂NEt / acetonitrile; H₂O / 3 h / Heating

3: 88 percent / DMSO, DCC, H₃PO₄ / 3 h / Ambient temperature

4: 2.58 g / t-BuOK / 2-methyl-propan-2-ol / 0.5 h / 40 °C

5: 84 percent / t-BuOK / benzene / 2 h / Ambient temperature

6: H₂ / 10percent Pd/C / methanol / 1 h

With phosphoric acid; potassium tert-butylate; hydrogen; lithium perchlorate; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; water; acetonitrile; tert-butyl alcohol; benzene;