Tert-butyl 2-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)-3-oxopropanoate

Base Information

Chemical Name:Tert-butyl 2-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)-3-oxopropanoate
CAS No.:40367-35-9
Molecular Formula:C₁₅H₁₅NO₅
Molecular Weight:289.288
Hs Code.:
NSC Number:151772
DSSTox Substance ID:DTXSID70302528
Mol file:40367-35-9.mol

Synonyms:40367-35-9;tert-butyl 2-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)-3-oxopropanoate;NSC 151772;NSC151772;tert-butyl 2-(1,3-dioxoisoindol-2-yl)-3-oxopropanoate;tert-butyl 2-formyl-2-phthalimido-acetate;SCHEMBL11387105;DTXSID70302528;NSC-151772;FT-0730251

Suppliers and Price of Tert-butyl 2-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)-3-oxopropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Tert-butyl 2-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)-3-oxopropanoate

Chemical Property:

Vapor Pressure:7.98E-07mmHg at 25°C
Boiling Point:406.7°Cat760mmHg
Flash Point:199.8°C
Density:1.305g/cm³
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:289.09502258
Heavy Atom Count:21
Complexity:455

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)C(C=O)N1C(=O)C2=CC=CC=C2C1=O

Technology Process of Tert-butyl 2-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)-3-oxopropanoate

There total 2 articles about Tert-butyl 2-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6297-93-4
tert-butyl 2-(1,3-dioxoisoindolin-2-yl)acetate

: 40367-35-9
3-oxo-2-phthalimido-propionic acid tert-butyl ester

Guidance literature:: With sodium hydride; benzene;
DOI:10.1021/ja01630a043

Reference yield:

: 6780-38-7
N-phthaloylglycine chloride

: 40367-35-9
3-oxo-2-phthalimido-propionic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; dichloromethane

2: benzene; sodium hydride

With dichloromethane; sodium hydride; triethylamine; benzene;
DOI:10.1021/ja01630a043

Reference yield:

: 40367-35-9
3-oxo-2-phthalimido-propionic acid tert-butyl ester

: 1057-37-0,1105-48-2
(4S)-2t-[(R)-tert-butoxycarbonyl-(2-phenoxy-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4r-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium acetate; aqueous ethanol

2: dioxane; N₂H₄+H₂O / Behandeln des Reaktionsprodukts mit Essigsaeure und wss. HCl

3: triethylamine; CH₂Cl₂

With 1,4-dioxane; ethanol; dichloromethane; sodium acetate; hydrazine hydrate; triethylamine;
DOI:10.1021/ja01521a044