1-(6-Amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-2,3-dihydroxyribofuranuronamide diacetate

Base Information

Chemical Name:1-(6-Amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-2,3-dihydroxyribofuranuronamide diacetate
CAS No.:58048-24-1
Molecular Formula:C17H20N6O6
Molecular Weight:404.43
Hs Code.:
Nikkaji Number:J342.247J
Wikidata:Q76151066

Synonyms:BRN 0594267;1-(6-Amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-2,3-dihydroxyribofuranuronamide diacetate;Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-2,3-dihydroxy-, diacetate;58048-24-1;C17H20N6O6;C17-H20-N6-O6;LS-143754;2-O,3-O-Diacetyl-1-(6-amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-beta-D-ribofuranuronamide

Suppliers and Price of 1-(6-Amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-2,3-dihydroxyribofuranuronamide diacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-(6-Amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-2,3-dihydroxyribofuranuronamide diacetate

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.77g/cm³
XLogP3:-0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:7
Exact Mass:404.14443238
Heavy Atom Count:29
Complexity:675

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1C(C(OC1C(=O)NC2CC2)N3C=NC4=C(N=CN=C43)N)OC(=O)C
Isomeric SMILES:CC(=O)O[C@H]1[C@H]([C@@H](O[C@@H]1C(=O)NC2CC2)N3C=NC4=C(N=CN=C43)N)OC(=O)C

Technology Process of 1-(6-Amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-2,3-dihydroxyribofuranuronamide diacetate

There total 2 articles about 1-(6-Amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-2,3-dihydroxyribofuranuronamide diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-24-7
acetic anhydride

: 50908-62-8
5-(N-cyclopropyl)carboxamidoadenosine

: 58048-24-1
2',3'-di-O-acetyladenosine-5'-(N-cyclopropyl)carboxamide

Guidance literature:: With pyridine; at 40 ℃; for 2h;
DOI:10.1021/jm00177a021

Reference yield:

: 41110-82-1
adenosine-5'-carboxylic acid 2-chloroethyl ester

: 58048-24-1
2',3'-di-O-acetyladenosine-5'-(N-cyclopropyl)carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1 h / Heating

2: pyridine / 2 h / 40 °C

With pyridine;
DOI:10.1021/jm00177a021