Carbamic acid, [1,6-dihydro-2-(4-methoxyphenyl)-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-ox o-1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester

Base Information

Chemical Name:Carbamic acid, [1,6-dihydro-2-(4-methoxyphenyl)-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-ox o-1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester
CAS No.:184709-75-9
Molecular Formula:C31H27F3N4O6
Molecular Weight:608.574
Hs Code.:
Mol file:184709-75-9.mol

Carbamic acid,
[1,6-dihydro-2-(4-methoxyphenyl)-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-ox
o-1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester

Synonyms:

Suppliers and Price of Carbamic acid, [1,6-dihydro-2-(4-methoxyphenyl)-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-ox o-1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Carbamic acid, [1,6-dihydro-2-(4-methoxyphenyl)-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-ox o-1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Carbamic acid, [1,6-dihydro-2-(4-methoxyphenyl)-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-ox o-1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester

There total 4 articles about Carbamic acid, [1,6-dihydro-2-(4-methoxyphenyl)-6-oxo-1-[2-oxo-2-[[3,3,3-trifluoro-2-ox o-1-(phenylmethyl)propyl]amino]ethyl]-5-pyrimidinyl]-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 184711-50-0
2-[5-Benzyloxycarbonylamino-2-(4-methoxyphenyl)-6-oxo-1,6-dihydro-1-pyrimidyl]-N-(1-benzyl-3,3,3-trifluoro-2-hydroxypropyl)acetamide

: 184709-75-9
2-[5-benzyloxycarbonylamino-2-(4-methoxyphenyl)-6-oxo-1,6-dihydro-1-pyrimidyl]-N-(1-benzyl-3,3,3-trifluoro-2-oxopropyl)-acetamide

Guidance literature:: With dichloro-acetic acid; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dimethyl sulfoxide; toluene; at 20 ℃;
DOI:10.1016/S0968-0896(00)00244-3

Reference yield:

: 124044-49-1
3-amino-1,1,1-trifluoro-4-phenyl-2-butanol

: 184709-75-9
2-[5-benzyloxycarbonylamino-2-(4-methoxyphenyl)-6-oxo-1,6-dihydro-1-pyrimidyl]-N-(1-benzyl-3,3,3-trifluoro-2-oxopropyl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: HOBT; EDC / dimethylformamide / 20 °C

2: EDC; Cl₂CHCO₂H / dimethylsulfoxide; toluene / 20 °C

With dichloro-acetic acid; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dimethyl sulfoxide; N,N-dimethyl-formamide; toluene; 1: condensation / 2: oxidation;
DOI:10.1016/S0968-0896(00)00244-3

Reference yield:

: 148748-41-8
[5-benzyloxycarbonylamino-2-(4-methoxyphenyl)-6-oxo-1,6-dihydro-1-pyrimidinyl]acetic acid

: 184709-75-9
2-[5-benzyloxycarbonylamino-2-(4-methoxyphenyl)-6-oxo-1,6-dihydro-1-pyrimidyl]-N-(1-benzyl-3,3,3-trifluoro-2-oxopropyl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: HOBT; EDC / dimethylformamide / 20 °C

2: EDC; Cl₂CHCO₂H / dimethylsulfoxide; toluene / 20 °C

With dichloro-acetic acid; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dimethyl sulfoxide; N,N-dimethyl-formamide; toluene; 1: condensation / 2: oxidation;
DOI:10.1016/S0968-0896(00)00244-3