N-(3,4-dimethoxyphenethyl)-2-iodoacetamide

Base Information

Chemical Name:N-(3,4-dimethoxyphenethyl)-2-iodoacetamide
CAS No.:184844-79-9
Molecular Formula:C12H16INO3
Molecular Weight:349.168
Hs Code.:
DSSTox Substance ID:DTXSID00395645
Nikkaji Number:J2.323.377K
Wikidata:Q82195842
Mol file:184844-79-9.mol

Synonyms:N-(3,4-dimethoxyphenethyl)-2-iodoacetamide;184844-79-9;N-[2-(3,4-dimethoxyphenyl)ethyl]-2-iodoacetamide;MS-0448;SCHEMBL9050505;DTXSID00395645;AKOS005107456;SR-01000309770;SR-01000309770-1

Suppliers and Price of N-(3,4-dimethoxyphenethyl)-2-iodoacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-(3,4-dimethoxyphenethyl)-2-iodoacetamide

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:349.01749
Heavy Atom Count:17
Complexity:238

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CCNC(=O)CI)OC

Technology Process of N-(3,4-dimethoxyphenethyl)-2-iodoacetamide

There total 2 articles about N-(3,4-dimethoxyphenethyl)-2-iodoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 14301-31-6
2-chloro-N-(2-(3,4-dimethoxyphenyl)ethyl)acetamide

: 184844-79-9
N-[2-(3,4-dimethoxy-phenyl)-ethyl]-2-iodo-acetamide

Guidance literature:: With sodium iodide; In butanone; for 2h; Heating;
DOI:10.1021/ol0607185

Reference yield:

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 184844-79-9
N-[2-(3,4-dimethoxy-phenyl)-ethyl]-2-iodo-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / N,N-dimethylaniline / CH₂Cl₂ / 1 h / 0 °C

2: 95 percent / NaI / butan-2-one / 2 h / Heating

With N,N-dimethyl-aniline; sodium iodide; In dichloromethane; butanone;
DOI:10.1021/ol0607185

Reference yield: 91.0%

: 184844-79-9
N-[2-(3,4-dimethoxy-phenyl)-ethyl]-2-iodo-acetamide

: 86488-10-0
5-ethylenedioxy-2-hydroxycyclohex-1-enecarboxylic acid methyl ester

: 894422-50-5
C₂₂H₂₉NO₈

Guidance literature:: 5-ethylenedioxy-2-hydroxycyclohex-1-enecarboxylic acid methyl ester; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.5h;

N-[2-(3,4-dimethoxy-phenyl)-ethyl]-2-iodo-acetamide; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1021/ol0607185