2-(2-Aminophenoxy)-N-methyl-N-phenylacetamide

Base Information

Chemical Name:2-(2-Aminophenoxy)-N-methyl-N-phenylacetamide
CAS No.:184870-82-4
Molecular Formula:C15H16N2O2
Molecular Weight:256.304
Hs Code.:
DSSTox Substance ID:DTXSID201251880

Synonyms:SCHEMBL8020586;DTXSID201251880;AKOS000127512;2-(2-AMINOPHENOXY)-N-METHYL-N-PHENYLACETAMIDE;184870-82-4

Suppliers and Price of 2-(2-Aminophenoxy)-N-methyl-N-phenylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(2-Aminophenoxy)-N-methyl-N-phenylacetamide

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:256.121177757
Heavy Atom Count:19
Complexity:290

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C1=CC=CC=C1)C(=O)COC2=CC=CC=C2N

Technology Process of 2-(2-Aminophenoxy)-N-methyl-N-phenylacetamide

There total 3 articles about 2-(2-Aminophenoxy)-N-methyl-N-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 183180-14-5
N-methyl-N-phenyl-2-(2-nitrophenoxy)acetamide

: 184870-82-4
N-methyl-N-phenyl-2-(2-aminophenoxy)acetamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 2.5h; under 760 Torr;
DOI:10.1248/cpb.47.755

Reference yield:

: 1878-87-1
2-nitrophenoxyacetic acid

: 184870-82-4
N-methyl-N-phenyl-2-(2-aminophenoxy)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / EDC*HCl, DMAP / CH₂Cl₂ / 72 h / Ambient temperature

2: 91 percent / H₂ / 5 percent Pd/C / methanol / 2.5 h / 760 Torr

With dmap; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1248/cpb.47.755

Reference yield:

: 100-61-8
N-methylaniline

: 184870-82-4
N-methyl-N-phenyl-2-(2-aminophenoxy)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / EDC*HCl, DMAP / CH₂Cl₂ / 72 h / Ambient temperature

2: 91 percent / H₂ / 5 percent Pd/C / methanol / 2.5 h / 760 Torr

With dmap; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1248/cpb.47.755