Carbamic acid, [2-[(2-amino-5-nitrophenyl)amino]-2-oxo-1-[(phenylmethoxy)methyl]ethyl] -, 1,1-dimethylethyl ester, (S)-

Base Information

Chemical Name:Carbamic acid, [2-[(2-amino-5-nitrophenyl)amino]-2-oxo-1-[(phenylmethoxy)methyl]ethyl] -, 1,1-dimethylethyl ester, (S)-
CAS No.:184951-75-5
Molecular Formula:C21H26N4O6
Molecular Weight:430.461
Hs Code.:
Mol file:184951-75-5.mol

Synonyms:

Suppliers and Price of Carbamic acid, [2-[(2-amino-5-nitrophenyl)amino]-2-oxo-1-[(phenylmethoxy)methyl]ethyl] -, 1,1-dimethylethyl ester, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Carbamic acid, [2-[(2-amino-5-nitrophenyl)amino]-2-oxo-1-[(phenylmethoxy)methyl]ethyl] -, 1,1-dimethylethyl ester, (S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, [2-[(2-amino-5-nitrophenyl)amino]-2-oxo-1-[(phenylmethoxy)methyl]ethyl] -, 1,1-dimethylethyl ester, (S)-

There total 1 articles about Carbamic acid, [2-[(2-amino-5-nitrophenyl)amino]-2-oxo-1-[(phenylmethoxy)methyl]ethyl] -, 1,1-dimethylethyl ester, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 23680-31-1
BOC-O-benzyl-L-serine

: 99-56-9
4-Nitrophenylene-1,2-diamine

: 184951-75-5
[(S)-1-(2-Amino-5-nitro-phenylcarbamoyl)-2-benzyloxy-ethyl]-carbamic acid tert-butyl ester

Guidance literature:: With 4-methyl-morpholine; isobutyl chloroformate; Yield given. Multistep reaction; 1) THF, -20 deg C, 10 min; 2) THF, -15 deg C, 2 h, rt, overnight;
DOI:10.1021/jo961245q

Reference yield: 84.0%

: 184951-75-5
[(S)-1-(2-Amino-5-nitro-phenylcarbamoyl)-2-benzyloxy-ethyl]-carbamic acid tert-butyl ester

: 184951-82-4
[(S)-1-(2-Amino-5-nitro-phenylthiocarbamoyl)-2-benzyloxy-ethyl]-carbamic acid tert-butyl ester

Guidance literature:: With tetraphosphorus decasulfide; sodium carbonate; In tetrahydrofuran; 1) 0 deg C, 30 min, 2.) rt, 2.5 h;
DOI:10.1021/jo961245q

Reference yield:

: 184951-75-5
[(S)-1-(2-Amino-5-nitro-phenylcarbamoyl)-2-benzyloxy-ethyl]-carbamic acid tert-butyl ester

: (S)-2-((S)-3-Benzyloxy-2-tert-butoxycarbonylamino-thiopropionylamino)-3-phenyl-propionic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / P₄S₁₀, Na₂CO₃ / tetrahydrofuran / 1) 0 deg C, 30 min, 2.) rt, 2.5 h

2: 83 percent / NaNO₂ / acetic acid; H₂O / 0.5 h / 0 °C

3: tetrahydrofuran / 0.67 h / 0 °C

With tetraphosphorus decasulfide; sodium carbonate; sodium nitrite; In tetrahydrofuran; water; acetic acid;
DOI:10.1021/jo961245q