5H-[1]Benzopyrano[2,3-b]pyridin-5-ol

Base Information

• Chemical Name: 5H-[1]Benzopyrano[2,3-b]pyridin-5-ol
• CAS No.: 6722-09-4
• Molecular Formula: C12H9NO2
• Molecular Weight: 199.209
• Hs Code.: 2934999090
• Mol file: 6722-09-4.mol

Synonyms:5H-chromeno[2,3-b]pyridin-5-ol;

Chemical Property of 5H-[1]Benzopyrano[2,3-b]pyridin-5-ol

Chemical Property:

• Vapor Pressure: 6.43E-06mmHg at 25°C
• Melting Point: 149.5-150.0 °C (decomp)
• Boiling Point: 363.4°Cat760mmHg
• PKA: 12.18±0.20(Predicted)
• Flash Point: 173.6°C
• PSA: 42.35000
• Density: 1.352g/cm³
• LogP: 2.26900

Purity/Quality:

98%,99%, ^*data from raw suppliers

5H-[1]-BENZOPYRANO[2,3-B]PYRIDIN-5-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 5H-[1]Benzopyrano[2,3-b]pyridin-5-ol

There total 2 articles about 5H-[1]Benzopyrano[2,3-b]pyridin-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5H-benzopyrano[2,3-b]pyridin-5-one (6537-46-8) → 5H-<1>benzopyrano<2,3-b>pyridin-5-ol (6722-09-4)

Guidance literature:

With sodium amalgam; ethanol;

DOI:10.1039/jr9520002057

Reference yield:

2-phenoxypyridine-3-carboxylic acid (35620-71-4) → 5H-<1>benzopyrano<2,3-b>pyridin-5-ol (6722-09-4)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃

2: sodium-amalgam; ethanol

With sodium amalgam; ethanol; trichlorophosphate;

DOI:10.1039/jr9520002057

Reference yield: 60.0%

5H-<1>benzopyrano<2,3-b>pyridin-5-ol (6722-09-4) + salicylaldehyde (90-02-8) + aniline (62-53-3) → N-phenylsalicylaldimine (779-84-0) + C18H14N2O + 2-hydroxybenzylidene-4-(5H-benzopyrano[2,3-b]pyridin-5-yl)aniline

Guidance literature:

With acetic acid; at 90 ℃; for 0.166667h;

DOI:10.1134/S1070363219040042

upstream raw materials:

5H-benzopyrano[2,3-b]pyridin-5-one

2-phenoxypyridine-3-carboxylic acid

Downstream raw materials:

(5S)-2-phenyl-α,α-dimethyl-N-(1,3,4-thiadiazol-2-yl)-5H-[1]benzopyrano[2,3-b]pyridin-5-acetamide

N-phenylsalicylaldimine