5-BROMO-2,4-DIAMINO-6-HYDROXYPYRIMIDINE

Base Information

• Chemical Name: 5-BROMO-2,4-DIAMINO-6-HYDROXYPYRIMIDINE
• CAS No.: 6312-72-7
• Molecular Formula: C4H5 Br N4 O
• Molecular Weight: 205.014
• Hs Code.: 2933599090
• Mol file: 6312-72-7.mol

Synonyms:4(1H)-Pyrimidinone,2,6-diamino-5-bromo- (9CI); 4(3H)-Pyrimidinone, 2,6-diamino-5-bromo- (7CI);4-Pyrimidinol, 2,6-diamino-5-bromo- (6CI,8CI);2,4-Diamino-6-hydroxy-5-bromopyrimidine;5-Bromo-2,4-diamino-6-hydroxypyrimidine;5-Bromo-2,6-diaminopyrimidin-4(3H)-one; NSC 40393; NSC 67304; NSC 9303

Chemical Property of 5-BROMO-2,4-DIAMINO-6-HYDROXYPYRIMIDINE

Chemical Property:

• Vapor Pressure: 0.00575mmHg at 25°C
• Melting Point: 265°C
• Boiling Point: 273.4°C at 760 mmHg
• PKA: 8.84±0.50(Predicted)
• Flash Point: 119.1°C
• PSA: 98.05000
• Density: 2.52g/cm³
• LogP: 1.27150
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-2,4-diamino-6-hydroxypyrimidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.
• Hazard Codes: R36/37/38:Irritating to eyes, respiratory system and skin.
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36:Wear suitable prot

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-BROMO-2,4-DIAMINO-6-HYDROXYPYRIMIDINE

There total 5 articles about 5-BROMO-2,4-DIAMINO-6-HYDROXYPYRIMIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,6-diaminopyrimidin-4-ol (56-06-4) → 5-bromo-2,4-diamino-6-hydroxypyrimidine (6312-72-7)

Guidance literature:

With bromine; sodium hydrogencarbonate; In methanol; water; 2 h stirring, then standing overnight;

DOI:10.1002/jhet.5570170747

Reference yield: 39.0%

→ 5-bromo-2,6-diamino-4(3H)-pyrimidinone (6312-72-7)

Guidance literature:

Reference yield:

thioxo-acetic acid (97925-57-0) → 5-bromo-2,6-diamino-4(3H)-pyrimidinone (6312-72-7)

Guidance literature:

With hydrogenchloride; In ethanol; dichloromethane;

upstream raw materials:

2,6-diamino-3H-pyrimidin-4-one

thioxo-acetic acid

2,6-diaminopyrimidin-4-ol

Downstream raw materials:

2-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylmercapto)-benzoic acid

2,5-diaminothiazolo<4,5-d>pyrimidin-7(6H)-one

(S)-6-methyl-5,6,7,8-tetrahydropterin

(S)-7-methyl-5,6,7,8-tetrahydropterin