4-amino-N-(2,6-dimethylphenyl)benzenesulfonamide

Base Information

• Chemical Name: 4-amino-N-(2,6-dimethylphenyl)benzenesulfonamide
• CAS No.: 6973-47-3
• Molecular Formula: C14H16N2O2S
• Molecular Weight: 276.35
• Hs Code.: 2935009090
• NSC Number: 42168
• DSSTox Substance ID: DTXSID80285530
• Wikidata: Q82020935
• Mol file: 6973-47-3.mol

Synonyms:4-amino-N-(2,6-dimethylphenyl)benzenesulfonamide;6973-47-3;4-amino-N-(2,6-dimethylphenyl)benzene-1-sulfonamide;NSC42168;n1-(2,6-dimethylphenyl)-4-aminobenzene-1-sulfonamide;Sulfanilo-2,6-xylidide;Oprea1_774617;SCHEMBL3844757;DTXSID80285530;CCG-42342;NSC-42168;STL032646;AKOS000144104;SB81508;CS-0250442;EN300-50904;SR-01000632349-1;Z57708666

Chemical Property of 4-amino-N-(2,6-dimethylphenyl)benzenesulfonamide

Chemical Property:

• Vapor Pressure: 2.62E-08mmHg at 25°C
• Boiling Point: 450.5°C at 760 mmHg
• Flash Point: 226.3°C
• PSA: 80.57000
• Density: 1.295g/cm³
• LogP: 4.42140
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 276.09324893
• Heavy Atom Count: 19
• Complexity: 373

Purity/Quality:

98%min ^*data from raw suppliers

4-Amino-N-(2,6-dimethylphenyl)benzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=CC=C1)C)NS(=O)(=O)C2=CC=C(C=C2)N

Technology Process of 4-amino-N-(2,6-dimethylphenyl)benzenesulfonamide

There total 3 articles about 4-amino-N-(2,6-dimethylphenyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-acetyl-sulfanilic acid-(2,6-dimethyl-anilide) (39925-91-2) → 4-amino-N-(2,6-dimethylphenyl)benzenesulfonamide (6973-47-3)

Guidance literature:

With sodium hydroxide;

Reference yield:

2,6-dimethylaniline (87-62-7) → 4-amino-N-(2,6-dimethylphenyl)benzenesulfonamide (6973-47-3)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone; pyridine

2: aq. NaOH solution

With pyridine; sodium hydroxide; acetone;

Reference yield:

p-acetylaminobenzenesulfonyl chloride (121-60-8) → 4-amino-N-(2,6-dimethylphenyl)benzenesulfonamide (6973-47-3)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone; pyridine

2: aq. NaOH solution

With pyridine; sodium hydroxide; acetone;

upstream raw materials:

N-acetyl-sulfanilic acid-(2,6-dimethyl-anilide)

2,6-dimethylaniline

p-acetylaminobenzenesulfonyl chloride