4-Bromo-2-(2-oxocyclopentyloxy)anisole

Base Information

Chemical Name:4-Bromo-2-(2-oxocyclopentyloxy)anisole
CAS No.:185244-57-9
Molecular Formula:C12H13BrO3
Molecular Weight:285.137
Hs Code.:
DSSTox Substance ID:DTXSID50447401
Mol file:185244-57-9.mol

Synonyms:4-Bromo-2-(2-oxocyclopentyloxy)anisole;185244-57-9;SCHEMBL5722812;DTXSID50447401;BIUHJCSPFGAWEZ-UHFFFAOYSA-N;4-Methoxy-3-(2-oxocyclopentyloxy)bromobenzene

Suppliers and Price of 4-Bromo-2-(2-oxocyclopentyloxy)anisole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Bromo-2-(2-oxocyclopentyloxy)anisole

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:284.00481
Heavy Atom Count:16
Complexity:257

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)Br)OC2CCCC2=O

Technology Process of 4-Bromo-2-(2-oxocyclopentyloxy)anisole

There total 4 articles about 4-Bromo-2-(2-oxocyclopentyloxy)anisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 694-28-0
2-chlorocyclopentanone

: 37942-01-1
5-bromo-2-methoxyphenol

: 185244-57-9
4-Methoxy-3-(2-oxocyclopentyloxy)bromobenzene

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 2.5h;
DOI:10.1021/jm010838c

Reference yield:

: 694-28-0
2-chlorocyclopentanone

destined water: destined water

: 37942-01-1
5-bromo-2-methoxyphenol

: 185244-57-9
4-Methoxy-3-(2-oxocyclopentyloxy)bromobenzene

Guidance literature:: With potassium carbonate; In N-methyl-acetamide; ethyl acetate;

Reference yield:

: 25016-01-7
5-bromo-2-methoxybenzaldehyde

: 185244-57-9
4-Methoxy-3-(2-oxocyclopentyloxy)bromobenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: 3-chloroperoxybenzoic acid / CH₂Cl₂ / 72 h / 0 - 20 °C

1.2: 92 percent / 2 M NaOH / diethyl ether

2.1: 69 percent / K₂CO₃ / dimethylformamide / 2.5 h / 60 °C

With potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; N,N-dimethyl-formamide; 1.1: Baeyer-Villiger oxidation;
DOI:10.1021/jm010838c