9,10-Epoxy-7,8-dihydroxy-7,8,9,10-tetrahydro-5-methylchrysene

Base Information

Chemical Name:9,10-Epoxy-7,8-dihydroxy-7,8,9,10-tetrahydro-5-methylchrysene
CAS No.:81851-67-4
Deprecated CAS:96790-41-9
Molecular Formula:C19H16O3
Molecular Weight:292.3285
Hs Code.:
Nikkaji Number:J874.309F
Mol file:81851-67-4.mol

Synonyms:7,8-DETMC;9,10-epoxy-7,8-dihydroxy-7,8,9,10-tetrahydro-5-methylchrysene;trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydro-5-methylchrysene

Suppliers and Price of 9,10-Epoxy-7,8-dihydroxy-7,8,9,10-tetrahydro-5-methylchrysene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 9,10-Epoxy-7,8-dihydroxy-7,8,9,10-tetrahydro-5-methylchrysene

Chemical Property:

Vapor Pressure:7.33E-14mmHg at 25°C
Boiling Point:570.6°Cat760mmHg
Flash Point:298.9°C
PSA：52.99000
Density:1.429g/cm³
LogP:3.14920
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:292.109944368
Heavy Atom Count:22
Complexity:452

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C3C(O3)C(C2O)O)C4=C1C5=CC=CC=C5C=C4
Isomeric SMILES:CC1=CC2=C([C@H]3[C@H](O3)[C@@H]([C@H]2O)O)C4=C1C5=CC=CC=C5C=C4

Technology Process of 9,10-Epoxy-7,8-dihydroxy-7,8,9,10-tetrahydro-5-methylchrysene

There total 18 articles about 9,10-Epoxy-7,8-dihydroxy-7,8,9,10-tetrahydro-5-methylchrysene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 101349-65-9
9α-bromo-7β,8α,10β-trihydroxy-7,8,9,10-tetrahydro-5-methylchrysene

: 81851-67-4,96790-41-9,97170-08-6,98508-99-7,111901-41-8,111901-42-9,111901-43-0
trans-7,8-dihydroxy-syn-9,10-epoxy-5-methyl-7,8,9,10-tetrahydrochrysene

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; tert-butyl alcohol; for 0.5h; Ambient temperature;
DOI:10.1021/jo00359a006

Reference yield: 31.0%

: 74206-63-6
trans-7,8-Dihydro-7,8-dihydroxy-5-methylchrysene

: 81851-67-4
7β,8α-Dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydro-5-methylchrysene

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; for 2h; Ambient temperature;
DOI:10.1021/jo00176a033

Reference yield:

: 27343-29-9
7-oxo-7,8,9,10-tetrahydro-5-methylchrysene

: 81851-67-4,96790-41-9,97170-08-6,98508-99-7,111901-41-8,111901-42-9,111901-43-0
trans-7,8-dihydroxy-syn-9,10-epoxy-5-methyl-7,8,9,10-tetrahydrochrysene

Guidance literature:: Multi-step reaction with 10 steps

1: NaBH₄ / tetrahydrofuran; methanol / 4.5 h

2: tosic acid / benzene / 1 h / Heating

3: 80 percent / I₂ / benzene / 4 h / Heating

4: 2.97 g / p-toluenesulfonic acid / benzene / 24 h / Heating

5: 71 percent / DDQ / benzene

6: 85 percent / glacial acetic acid, concd. HCl / 24 h / Heating

7: 82 percent / Adogen 464, Fremy's salt, KH₂PO₄ / H₂O / 1 h

8: 91 percent / NaBH₄, O₂ / ethanol / 28 h

9: 61 percent / N-bromosuccinimide / dimethylsulfoxide; H₂O / 1 h / Ambient temperature

10: 76 percent / potasium tert-butoxide / tetrahydrofuran; 2-methyl-propan-2-ol / 0.5 h / Ambient temperature

With hydrogenchloride; sodium tetrahydroborate; potassium dihydrogenphosphate; N-Bromosuccinimide; adogen 464; potassiuim nitrosodisulfonate; potassium tert-butylate; iodine; oxygen; toluene-4-sulfonic acid; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; methanol; ethanol; water; dimethyl sulfoxide; tert-butyl alcohol; benzene;
DOI:10.1021/jo00359a006