3-(2-Fluoro-4,5-dihydroxyphenyl)-2-methylalanine

Base Information

Chemical Name:3-(2-Fluoro-4,5-dihydroxyphenyl)-2-methylalanine
CAS No.:6482-05-9
Molecular Formula:C₁₀H₁₂FNO₄
Molecular Weight:229.208
Hs Code.:2922509090
DSSTox Substance ID:DTXSID60215113
Wikidata:Q83091070
Mol file:6482-05-9.mol

Synonyms:3-(2-fluoro-4,5-dihydroxyphenyl)-2-methylalanine;FMEDOPA

Suppliers and Price of 3-(2-Fluoro-4,5-dihydroxyphenyl)-2-methylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-(2-Fluoro-4,5-dihydroxyphenyl)-2-methylalanine

Chemical Property:

Vapor Pressure:3.75E-09mmHg at 25°C
Boiling Point:457.2°C at 760 mmHg
Flash Point:230.3°C
PSA：103.78000
Density:1.481g/cm³
LogP:1.28170
XLogP3:-1.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:229.07503603
Heavy Atom Count:16
Complexity:276

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC(=C(C=C1F)O)O)(C(=O)O)N
Isomeric SMILES:C[C@](CC1=CC(=C(C=C1F)O)O)(C(=O)O)N

Technology Process of 3-(2-Fluoro-4,5-dihydroxyphenyl)-2-methylalanine

There total 2 articles about 3-(2-Fluoro-4,5-dihydroxyphenyl)-2-methylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7537-25-9
2-Amino-3-(2-fluoro-3,4-dimethoxy-phenyl)-2-methyl-propionic acid

: 6482-05-9
2-Amino-3-(2-fluoro-3,4-dihydroxy-phenyl)-2-methyl-propionic acid

Guidance literature:: With hydrogen bromide;
DOI:10.1021/jm00323a022

Reference yield:

: 7537-23-7
5-(2-fluoro-3,4-dimethoxy-benzyl)-5-methyl-imidazolidine-2,4-dione

: 6482-05-9
2-Amino-3-(2-fluoro-3,4-dihydroxy-phenyl)-2-methyl-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: aq. Ba(OH)2

2: aq. HBr

With barium dihydroxide; hydrogen bromide;
DOI:10.1021/jm00323a022