6-Methoxy-2-(4-methylphenyl)-1-benzothiophene

Base Information

Chemical Name:6-Methoxy-2-(4-methylphenyl)-1-benzothiophene
CAS No.:185414-69-1
Molecular Formula:C16H14OS
Molecular Weight:254.353
Hs Code.:
DSSTox Substance ID:DTXSID20708354
Wikidata:Q82642621
Mol file:185414-69-1.mol

Synonyms:185414-69-1;6-Methoxy-2-(4-methylphenyl)-1-benzothiophene;DTXSID20708354

Suppliers and Price of 6-Methoxy-2-(4-methylphenyl)-1-benzothiophene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6-Methoxy-2-(4-methylphenyl)-1-benzothiophene

Chemical Property:

XLogP3:4.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:254.07653624
Heavy Atom Count:18
Complexity:272

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=CC3=C(S2)C=C(C=C3)OC

Technology Process of 6-Methoxy-2-(4-methylphenyl)-1-benzothiophene

There total 5 articles about 6-Methoxy-2-(4-methylphenyl)-1-benzothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 90560-10-4
6-methoxy-benzo[b]thiophene

: 624-31-7
4-tolyl iodide

: 185414-69-1
6-methoxy-2-(p-tolyl)benzo[b]thiophene

Guidance literature:: With palladium diacetate; silver trifluoroacetate; trifluoroacetic acid; In water; at 20 ℃; for 48h; Inert atmosphere;
DOI:10.1016/j.bioorg.2021.104919

Reference yield:

: 90560-10-4
6-methoxy-benzo[b]thiophene

: 185414-69-1
6-methoxy-2-(p-tolyl)benzo[b]thiophene

Guidance literature:: Multi-step reaction with 2 steps

1.1: BuLi

1.2: B(OiPr)3

1.3: HCl

2.1: Na₂CO₃; Pd(PPh₃)4

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; sodium carbonate; 2.1: Suzuki coupling reaction;
DOI:10.1021/jm015577l