Chemical Property of 3-Fluoro-4-[[2-hydroxy-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)acetyl]amino]benzoic acid
Chemical Property:
- Boiling Point:590.9±50.0 °C(Predicted)
- PKA:3.92±0.10(Predicted)
- PSA：90.12000
- Density:1.241±0.06 g/cm3(Predicted)
- LogP:5.19450
- XLogP3:4.9
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:4
- Exact Mass:399.18458647
- Heavy Atom Count:29
- Complexity:634
- Purity/Quality:
-
97% *data from raw suppliers
BMS 961 *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CC1(CCC(C2=C1C=CC(=C2)C(C(=O)NC3=C(C=C(C=C3)C(=O)O)F)O)(C)C)C
-
Uses
BMS961 is a potent and selective retinoic acid receptor gamma (RARγ) agonist with IC50 values of 30 nM. RARγ belongs to the family of nuclear receptors which regulates transcription. in vitro, application of BMS961on mouse ear skin was found to cause a significant increase of thymic stromal lymphopoietin (TSLP) transcripts1.
