2-amino-3-(6-hydroxy-1H-indol-3-yl)propanoic Acid

Base Information

• Chemical Name: 2-amino-3-(6-hydroxy-1H-indol-3-yl)propanoic Acid
• CAS No.: 18749-30-9
• Molecular Formula: C11H12N2O3
• Molecular Weight: 220.22500
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID30432537
• Nikkaji Number: J886.496I
• Wikidata: Q82246602
• Mol file: 18749-30-9.mol

Synonyms:18749-30-9;2-amino-3-(6-hydroxy-1H-indol-3-yl)propanoic Acid;6-Hydroxy-DL-tryptophan;MFCD01544817;6-HYDROXY-TRYPTOPHAN;SCHEMBL179962;2-Amino-3-(6-hydroxy-1H-indol-3-yl)propanoicacid;SCHEMBL18029338;DTXSID30432537;SY246889;CS-0448887;FT-0778009;6-Hydroxy-tryptophan (H-DL-Trp(6-OH)-OH);A880577

Chemical Property of 2-amino-3-(6-hydroxy-1H-indol-3-yl)propanoic Acid

Chemical Property:

• Melting Point: 283-286 °C
• Boiling Point: 520.6±50.0 °C(Predicted)
• PKA: 2.23±0.10(Predicted)
• PSA: 99.34000
• Density: 1.484±0.06 g/cm3(Predicted)
• LogP: 1.52820
• Storage Temp.: 2-8°C
• XLogP3: -1.2
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 220.08479225
• Heavy Atom Count: 16
• Complexity: 272

Purity/Quality:

97% ^*data from raw suppliers

2-AMINO-3-(6-HYDROXY-1H-INDOL-3-YL)PROPANOIC ACID 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C1O)NC=C2CC(C(=O)O)N

Technology Process of 2-amino-3-(6-hydroxy-1H-indol-3-yl)propanoic Acid

There total 2 articles about 2-amino-3-(6-hydroxy-1H-indol-3-yl)propanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

C12H14N2O3 → 6-hydroxytryptophan (18749-30-9,1398507-94-2)

Guidance literature:

With lithium hydroxide monohydrate; In tetrahydrofuran; water; isopropyl alcohol; at 5 - 7 ℃; for 6h;

DOI:10.1021/mp500312t

Reference yield:

→ 6-hydroxytryptophan (18749-30-9,1398507-94-2)

Guidance literature:

Tryptophan, Ethylendiamintetraacetat, FeSO4, Ascorbinsaeure, Phosphatpuffer, (Durchleiten von Luftsauerstoff); neben anderen Verbb.;

DOI:10.1515/znb-1968-0708