Benzenemethanamine, N-(1-cyclohexylethylidene)-

Base Information

• Chemical Name: Benzenemethanamine, N-(1-cyclohexylethylidene)-
• CAS No.: 188645-15-0
• Molecular Formula: C15H21N
• Molecular Weight: 215.338
• DSSTox Substance ID: DTXSID60453876
• Nikkaji Number: J619.969K,J620.021D,J620.022B
• Mol file: 188645-15-0.mol

Synonyms:Benzenemethanamine, N-(1-cyclohexylethylidene)-;188645-15-0;SCHEMBL8909214;DTXSID60453876;(E)-N-Benzyl-1-cyclohexylethane-1-imine;(Z)-N-Benzyl-1-cyclohexylethane-1-imine;N-Benzyl-alpha-methylcyclohexanemethanimine

Chemical Property of Benzenemethanamine, N-(1-cyclohexylethylidene)-

Chemical Property:

• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 215.167399674
• Heavy Atom Count: 16
• Complexity: 220

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NCC1=CC=CC=C1)C2CCCCC2

Technology Process of Benzenemethanamine, N-(1-cyclohexylethylidene)-

There total 1 articles about Benzenemethanamine, N-(1-cyclohexylethylidene)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Cyclohexyl methyl ketone (823-76-7) + benzylamine (100-46-9) → N-(1-cyclohexylethylidene)benzylamine (188645-15-0)

Guidance literature:

In dichloromethane; at 80 ℃; for 24h; Inert atmosphere; Molecular sieve; Sealed tube;

DOI:10.1021/jacs.1c07402

Reference yield: 38.0%

di-tert-butyl dicarbonate (24424-99-5) + N-(1-cyclohexylethylidene)benzylamine (188645-15-0) → tert-Butyl benzyl(1-cyclohexylvinyl)carbamate

Guidance literature:

With triethylamine; In benzene; at 20 ℃; for 1.5h;

DOI:10.1055/s-2001-15075

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + N-(1-cyclohexylethylidene)benzylamine (188645-15-0) → C20H31NO2 + C20H31NO2

Guidance literature:

With C₄₃H₃₀BF₁₅N₂O₂RuS; hydrogen; In 1,2-dichloro-ethane; at 40 ℃; for 10h; under 38002.6 Torr; optical yield given as %ee; enantioselective reaction; Autoclave;

DOI:10.1016/j.tet.2012.03.019

upstream raw materials:

Cyclohexyl methyl ketone

benzylamine

Downstream raw materials:

Benzyl-((S)-1-cyclohexyl-ethyl)-amine

(R)-N-benzyl-1-cyclohexylethylamine

(S)-N-benzyl-α-cyclohexylethylamine