4-Chloro-6-ethylquinoline

Base Information

Chemical Name:4-Chloro-6-ethylquinoline
CAS No.:188758-77-2
Molecular Formula:C11H10ClN
Molecular Weight:191.65700
Hs Code.:
European Community (EC) Number:847-501-8
DSSTox Substance ID:DTXSID20440707
Wikidata:Q82257080
Mol file:188758-77-2.mol

Synonyms:4-Chloro-6-ethylquinoline;188758-77-2;Quinoline, 4-chloro-6-ethyl-;SCHEMBL14690592;DTXSID20440707;MFCD09787734;AKOS002683724;AB52108;CS-0448920;FT-0738776;EN300-67712

Suppliers and Price of 4-Chloro-6-ethylquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-chloro-6-ethylquinoline
50mg
$ 130.00

American Custom Chemicals Corporation
4-CHLORO-6-ETHYLQUINOLINE 95.00%
5MG
$ 504.47

AK Scientific
4-Chloro-6-ethylquinoline
250mg
$ 403.00

Total 7 raw suppliers

Chemical Property of 4-Chloro-6-ethylquinoline

Chemical Property:

Vapor Pressure:0.004mmHg at 25°C
Boiling Point:289.292oC at 760 mmHg
Flash Point:156.313oC
PSA：12.89000
Density:1.186g/cm3
LogP:3.45060
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:191.0501770
Heavy Atom Count:13
Complexity:172

Purity/Quality:

97% ^*data from raw suppliers

4-chloro-6-ethylquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC2=C(C=CN=C2C=C1)Cl

Technology Process of 4-Chloro-6-ethylquinoline

There total 3 articles about 4-Chloro-6-ethylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 188758-76-1,303121-13-3
6-Ethyl-1H-quinolin-4-one

: 188758-77-2
4-chloro-6-ethylquinoline

Guidance literature:: With trichlorophosphate; Heating;
DOI:10.1021/jm9607865

Reference yield:

: 111185-85-4,103802-41-1
6-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

: 188758-77-2
4-chloro-6-ethylquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / benzophenone / 275 °C

2: 92 percent / POCl₃ / Heating

With benzophenone; trichlorophosphate;
DOI:10.1021/jm9607865

Reference yield:

: 589-16-2
4-aminoethylbenzene

: 188758-77-2
4-chloro-6-ethylquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) 120 deg C, 1 h, 2.) Dowtherm A, reflux

2: 77 percent / benzophenone / 275 °C

3: 92 percent / POCl₃ / Heating

With benzophenone; trichlorophosphate;
DOI:10.1021/jm9607865