Technology Process of 17-(3'-thiophenyl)androstane-3,14-diol 3-glucopyranoside
There total 1 articles about 17-(3'-thiophenyl)androstane-3,14-diol 3-glucopyranoside which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
n-butyllithium;
Yield given. Multistep reaction;
1.) ether, -70 deg C, 1 h, 2.) benzene, -70 deg C, 30 min;
DOI:10.1016/0039-128X(90)90026-8
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 4-dimethylaminopyridine, pyridine / 96 h / Ambient temperature
2: calcium carbonate / acetone; H2O / 48 h / Heating
3: 92 percent / potassium hydroxide, H2 / 10percent palladium/calcium carbonate / methanol; ethanol / Ambient temperature; pH 9.5
4: 85 percent / mesyl chloride, pyridine / 4 h / 60 °C
With
pyridine; dmap; potassium hydroxide; hydrogen; methanesulfonyl chloride; calcium carbonate;
Lindlar's catalyst;
In
methanol; ethanol; water; acetone;
DOI:10.1016/0039-128X(90)90026-8
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 4-dimethylaminopyridine, pyridine / 96 h / Ambient temperature
2: calcium carbonate / acetone; H2O / 48 h / Heating
3: 92 percent / potassium hydroxide, H2 / 10percent palladium/calcium carbonate / methanol; ethanol / Ambient temperature; pH 9.5
With
pyridine; dmap; potassium hydroxide; hydrogen; calcium carbonate;
Lindlar's catalyst;
In
methanol; ethanol; water; acetone;
DOI:10.1016/0039-128X(90)90026-8
