6-amino-N-[(4-fluorophenyl)methyl]hexanamide

Base Information

Chemical Name:6-amino-N-[(4-fluorophenyl)methyl]hexanamide
CAS No.:189162-98-9
Molecular Formula:C13H19FN2O
Molecular Weight:238.305
Hs Code.:
DSSTox Substance ID:DTXSID80441114
Wikidata:Q82257713

Synonyms:6-amino-N-[(4-fluorophenyl)methyl]hexanamide;189162-98-9;Hexanamide, 6-amino-N-[(4-fluorophenyl)methyl]-;SCHEMBL15678793;DTXSID80441114;AKOS000197901;A1-05749

Suppliers and Price of 6-amino-N-[(4-fluorophenyl)methyl]hexanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6-amino-N-[(4-fluorophenyl)methyl]hexanamide

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:238.14814140
Heavy Atom Count:17
Complexity:216

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CNC(=O)CCCCCN)F

Technology Process of 6-amino-N-[(4-fluorophenyl)methyl]hexanamide

There total 1 articles about 6-amino-N-[(4-fluorophenyl)methyl]hexanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [5-(4-Fluoro-benzylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester

: 189162-98-9
6-Amino-hexanoic acid 4-fluoro-benzylamide

Guidance literature:: With hydrogenchloride; In 1,4-dioxane;

Reference yield: 78.0%

: 58521-49-6
(3S,4S)-4-(tert-butoxycarbonylamino)-3-hydroxy-6-methylheptanoic acid

: 189162-98-9
6-Amino-hexanoic acid 4-fluoro-benzylamide

: 189162-99-0
((S)-1-{(S)-2-[5-(4-Fluoro-benzylcarbamoyl)-pentylcarbamoyl]-1-hydroxy-ethyl}-3-methyl-butyl)-carbamic acid tert-butyl ester

Guidance literature:: With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In dichloromethane; 1) 0 deg C, 2) r.t., overnight;

Reference yield:

: 189162-98-9
6-Amino-hexanoic acid 4-fluoro-benzylamide

: (3S,4S)-4-[(S)-2-[(S)-2-Amino-3-(4-methoxy-phenyl)-propionylamino]-3-(1H-imidazol-4-yl)-propionylamino]-3-hydroxy-6-methyl-heptanoic acid [5-(4-fluoro-benzylcarbamoyl)-pentyl]-amide

Guidance literature:: Multi-step reaction with 7 steps

1: 78 percent / HOBt, DCCI / CH₂Cl₂ / 1) 0 deg C, 2) r.t., overnight

2: 4 M HCl / dioxane

3: 48 percent / HOBt, DCCI / CH₂Cl₂ / 1) 0 deg C, 2) r.t., overnight

4: 4 M HCl / dioxane

5: 90 percent / HOBt, DCCI / CH₂Cl₂ / 1) 0 deg C, 2) r.t., overnight

6: H₂ / 5percent PdO/BaSO₄ / methanol; acetic acid; H₂O / 12 h / 1551.4 Torr

7: 4 M HCl / dioxane

With hydrogenchloride; hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide; barium sulfate; trimethyleneglycol; In 1,4-dioxane; methanol; dichloromethane; water; acetic acid;