Technology Process of 3-Butyn-2-ol, 2-methyl-4-[4-[2-(4-pyridinyl)ethenyl]phenyl]-, (E)-
There total 6 articles about 3-Butyn-2-ol, 2-methyl-4-[4-[2-(4-pyridinyl)ethenyl]phenyl]-, (E)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine;
at 20 ℃;
for 15h;
DOI:10.1016/S0040-4020(02)01628-9
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 80 percent / ethanol / 48 h / sunlight
2: 71 percent / Cl2Pd(PPh3)2; cuprous iodide; HNEt2 / 15 h / 20 °C
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine;
In
ethanol;
DOI:10.1016/S0040-4020(02)01628-9
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 70 percent / N-bromosuccinimide; benzoyl peroxide / CCl4 / 16 h / Heating
2.1: 78 percent / toluene / 12 h / Heating
3.1: KOtBu / toluene / 0.5 h / 0 °C
3.2: 79 percent / toluene / 12 h / 20 °C
4.1: 80 percent / ethanol / 48 h / sunlight
5.1: 71 percent / Cl2Pd(PPh3)2; cuprous iodide; HNEt2 / 15 h / 20 °C
With
bis-triphenylphosphine-palladium(II) chloride; N-Bromosuccinimide; copper(l) iodide; potassium tert-butylate; diethylamine; dibenzoyl peroxide;
In
tetrachloromethane; ethanol; toluene;
3.2: Wittig reaction;
DOI:10.1016/S0040-4020(02)01628-9