N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide

Base Information

Chemical Name:N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide
CAS No.:120615-25-0
Molecular Formula:C₁₁H₁₂ClN₃O₂S
Molecular Weight:285.754
Hs Code.:2935009090
European Community (EC) Number:691-035-6
UNII:3IE84W82O5
DSSTox Substance ID:DTXSID20152934
Nikkaji Number:J704.409G
Wikidata:Q27094604
Metabolomics Workbench ID:148187
ChEMBL ID:CHEMBL489157
Mol file:120615-25-0.mol

Synonyms:CKI 7;CKI-7;N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide

Suppliers and Price of N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide
50mg
$ 625.00

TRC
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide
10mg
$ 150.00

SynQuest Laboratories
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide
5 mg
$ 280.00

SynQuest Laboratories
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide
10 mg
$ 440.00

SynQuest Laboratories
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide
25 mg
$ 920.00

Medical Isotopes, Inc.
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide
10 mg
$ 860.00

ChemScene
CKI-7(freebase) 99.31%
10mg
$ 150.00

ChemScene
CKI-7(freebase) 99.31%
5mg
$ 85.00

ChemScene
CKI-7(freebase) 99.31%
50mg
$ 625.00

ChemScene
CKI-7(freebase) 99.31%
25mg
$ 375.00

Total 14 raw suppliers

Chemical Property of N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide

Chemical Property:

Appearance/Colour:off-white crystalline solid
Vapor Pressure:4.04E-10mmHg at 25°C
Melting Point:188-190 ºC
Refractive Index:1.644
Boiling Point:499.7 °C at 760 mmHg
PKA:7.80±0.50(Predicted)
Flash Point:256 °C
PSA：93.46000
Density:1.432 g/cm³
LogP:3.29720
Storage Temp.:−20°C
Solubility.:H2O: 9 mg/mL
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:285.0338755
Heavy Atom Count:18
Complexity:371

Purity/Quality:

97% ^*data from raw suppliers

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=C2C=CN=CC2=C1S(=O)(=O)NCCN)Cl
Uses CKI-7 is found to have a potent inhibitory action against casein kinase 1 completely with respect to ATP and a much weaker effect on casein kinase 2 and other protein kinases.

Technology Process of N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide

There total 1 articles about N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: