2-(2-Chlorophenyl)-5-{[(methanesulfinyl)methyl]sulfanyl}-1,3,4-oxadiazole

Base Information

Chemical Name:2-(2-Chlorophenyl)-5-{[(methanesulfinyl)methyl]sulfanyl}-1,3,4-oxadiazole
CAS No.:189283-17-8
Molecular Formula:C₁₀H₉ClN₂O₂S₂
Molecular Weight:288.779
Hs Code.:
DSSTox Substance ID:DTXSID10571332

Synonyms:189283-17-8;DTXSID10571332;2-(2-Chlorophenyl)-5-{[(methanesulfinyl)methyl]sulfanyl}-1,3,4-oxadiazole

Suppliers and Price of 2-(2-Chlorophenyl)-5-{[(methanesulfinyl)methyl]sulfanyl}-1,3,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(2-Chlorophenyl)-5-{[(methanesulfinyl)methyl]sulfanyl}-1,3,4-oxadiazole

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:287.9793976
Heavy Atom Count:17
Complexity:283

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CS(=O)CSC1=NN=C(O1)C2=CC=CC=C2Cl

Technology Process of 2-(2-Chlorophenyl)-5-{[(methanesulfinyl)methyl]sulfanyl}-1,3,4-oxadiazole

There total 1 articles about 2-(2-Chlorophenyl)-5-{[(methanesulfinyl)methyl]sulfanyl}-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21128-88-1
chloromethyl methyl sulfoxide

: 23766-27-0
2-mercapto-5-(2-chlorophenyl)-1,3,4-oxadiazole

: 189283-17-8
2-(2-Chloro-phenyl)-5-methanesulfinylmethylsulfanyl-[1,3,4]oxadiazole

Guidance literature:: With sodium hydroxide; ethanol; Yield given. Multistep reaction; 2.) EtOH, reflux, 5 h;
DOI:10.1039/a605234g

Reference yield:

: 189283-17-8
2-(2-Chloro-phenyl)-5-methanesulfinylmethylsulfanyl-[1,3,4]oxadiazole

: (4R,5R)-5-[5-(2-Chloro-phenyl)-[1,3,4]oxadiazol-2-ylsulfanyl]-4-phenyl-[1,2,3]thiadiazolidine-2-carbothioic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaOMe / 1.) MeOH, RT, 2.) MeOH, RT

2: 60 percent / SOCl₂, pyridine / 8 h / Heating

With pyridine; thionyl chloride; sodium methylate;
DOI:10.1039/a605234g

Reference yield:

: 189283-17-8
2-(2-Chloro-phenyl)-5-methanesulfinylmethylsulfanyl-[1,3,4]oxadiazole

: (4R,5R)-4-(4-Chloro-phenyl)-5-[5-(2-chloro-phenyl)-[1,3,4]oxadiazol-2-ylsulfanyl]-[1,2,3]thiadiazolidine-2-carbothioic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaOMe / 1.) MeOH, RT, 2.) MeOH, RT

2: 62 percent / SOCl₂, pyridine / 8 h / Heating

With pyridine; thionyl chloride; sodium methylate;
DOI:10.1039/a605234g