2,4-Dihydroxy-7-methoxy-1,4-benzoxazin-3-one

Base Information

Chemical Name:2,4-Dihydroxy-7-methoxy-1,4-benzoxazin-3-one
CAS No.:15893-52-4
Molecular Formula:C₉H₉NO₅
Molecular Weight:211.174
Hs Code.:
UNII:TI783RU0DR
DSSTox Substance ID:DTXSID90936021
Nikkaji Number:J61.255C
Wikipedia:DIMBOA
Wikidata:Q1748422
Metabolomics Workbench ID:46720
ChEMBL ID:CHEMBL2269101
Mol file:15893-52-4.mol

Synonyms:2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one;DIMBOA

Suppliers and Price of 2,4-Dihydroxy-7-methoxy-1,4-benzoxazin-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DIMBOA
50mg
$ 845.00

TRC
DIMBOA
100mg
$ 1515.00

DC Chemicals
DIMBOA >98%
1 g
$ 1800.00

ChemScene
DIMBOA 99.39%
10mg
$ 165.00

ChemScene
DIMBOA 99.39%
5mg
$ 100.00

ChemScene
DIMBOA 99.39%
25mg
$ 360.00

ChemScene
DIMBOA 99.39%
50mg
$ 650.00

Arctom
2,4-Dihydroxy-7-methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one ≥98%
250mg
$ 1173.00

Arctom
2,4-Dihydroxy-7-methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one ≥98%
100mg
$ 781.00

Arctom
2,4-Dihydroxy-7-methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one ≥98%
1g
$ 2930.00

Total 54 raw suppliers

Chemical Property of 2,4-Dihydroxy-7-methoxy-1,4-benzoxazin-3-one

Chemical Property:

Vapor Pressure:2.64E-09mmHg at 25°C
Melting Point:150-155 °C
Refractive Index:1.658
Boiling Point:461.3 °C at 760 mmHg
PKA:7.59±0.40(Predicted)
Flash Point:232.8 °C
PSA：79.23000
Density:1.589 g/cm³
LogP:0.19320
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:211.04807239
Heavy Atom Count:15
Complexity:259

Purity/Quality:

99%, ^*data from raw suppliers

DIMBOA ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)N(C(=O)C(O2)O)O
Recent ClinicalTrials:Hyperbaric Oxygenation (HBO) in Traumatic Spinal Cord Injury. (EOS) - Pilot Study
Uses DIMBOA acts as an antifungal and antialgal agent in crops. The benzoxazinone group within the structure allows for these effects.

Technology Process of 2,4-Dihydroxy-7-methoxy-1,4-benzoxazin-3-one

There total 13 articles about 2,4-Dihydroxy-7-methoxy-1,4-benzoxazin-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 4-Hydroxy-7-methoxy-2-methoxymethoxy-4H-benzo[1,4]oxazin-3-one

: 15893-52-4,147802-15-1,147802-16-2,588716-65-8
2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one

Guidance literature:: With boron trichloride; In dichloromethane; at -40 - -5 ℃; for 1h;
DOI:10.1080/00032719808006490

Reference yield: 75.0%

: 151253-61-1
4-hydroxy-7-methoxy-2,3-dioxo-1,4-benzoxazine

: 15893-52-4,147802-15-1,147802-16-2,588716-65-8
2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one

Guidance literature:: With diisobutylaluminium hydride; In toluene; at -78 - 0 ℃; for 2h;
DOI:10.1055/s-1993-25936

Reference yield: 30.0%

: 55544-90-6,147802-07-1,147802-08-2
4-Hydroxy-2,7-dimethoxy-2H-1,4-benzoxazin-3(4H)-one

: 15893-52-4,147802-15-1,147802-16-2,588716-65-8
2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one

Guidance literature:: 4-Hydroxy-2,7-dimethoxy-2H-1,4-benzoxazin-3(4H)-one; With boron trichloride; In dichloromethane; at 20 ℃; for 2.5h;

With silver carbonate; In tetrahydrofuran; water; for 0.333333h;
DOI:10.3797/scipharm.aut-05-08